CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement. - Test2 - elhamkhani - TriplyDB

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement.

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement.

http://www.wikidata.org/entity/Q34985437

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Can follicular helper T cells be targeted to improve vaccine efficacy?Targeting microRNAs for immunomodulation Regulators of Tfh Cell Differentiation Synergistic effects of the immune checkpoint inhibitor CTLA-4 combined with the growth inhibitor lycorine in a mouse model of renal cell carcinoma.Follicular Helper T Cells in Autoimmunity.Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood.miR-424(322) reverses chemoresistance via T-cell immune response activation by blocking the PD-L1 immune checkpoint Characterization of T follicular helper cells in allogeneic normal pregnancy and PDL1 blockage-induced abortion.Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3+ T Cells.CD4 T cell differentiation in type 1 diabetes.Challenges and opportunities in targeting the CD28/CTLA-4 pathway in transplantation and autoimmunity.T follicular helper cells in the generation of alloantibody and graft rejection.Immune checkpoint inhibitors in lung cancer: past, present and future.T follicular regulatory cells.T Cell Cosignaling Molecules in Transplantation.Insights into the development and regulation of T follicular helper cells.CHAI and LATAIE: new genetic diseases of CTLA-4 checkpoint insufficiency.Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease.Belatacept As an Alternative to Calcineurin Inhibitors in Patients with Solid Organ Transplants.Immune deficiency and autoimmunity in patients with CTLA-4 (CD152) mutations.Signals that drive T follicular helper cell formation.Long-Term Outcomes in Belatacept- Versus Cyclosporine-Treated Recipients of Extended Criteria Donor Kidneys: Final Results From BENEFIT-EXT, a Phase III Randomized Study.Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection.Spontaneous germinal centers and autoimmunity.A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response.A distinct subpopulation of CD25- T-follicular regulatory cells localizes in the germinal centers.Foxp1 Negatively Regulates T Follicular Helper Cell Differentiation and Germinal Center Responses by Controlling Cell Migration and CTLA-4.Contemplating autoimmunity in the Aegean islands.Selective CD28 Blockade Results in Superior Inhibition of Donor-Specific T Follicular Helper Cell and Antibody Responses Relative to CTLA4-Ig.Dichotomous roles of co-stimulatory molecules in diabetes mellitus.Exaggerated follicular helper T-cell responses in patients with LRBA deficiency caused by failure of CTLA4-mediated regulation.Morphology of Immunomodulation in Breast Cancer Tumor Draining Lymph Nodes Depends on Stage and Intrinsic Subtype.CTLA‑4 interferes with the HBV‑specific T cell immune response (Review).T Cell/B Cell Collaboration and Autoimmunity: An Intimate Relationship A meta-analysis of the association between CTLA-4 genetic polymorphism and susceptibility of asthma Harnessing T Follicular Helper Cell Responses for HIV Vaccine Development T Follicular Regulatory Cells and Antibody Responses in Transplantation Role of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses Control of Germinal Center Responses by T-Follicular Regulatory Cells

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P2860

CTLA-4 controls follicular helper T-cell differentiation by regulating the strength of CD28 engagement.

http://www.wikidata.org/entity/Q34985437

description

2014 nî lūn-bûn

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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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name

CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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PNAS.1414576112

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Proceedings of the National Academy of Sciences of the United States of America

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CTLA-4 controls follicular hel ...... e strength of CD28 engagement.

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Alexandros Kogimtzis

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Chantelle Bowers

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Chun Jing Wang

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Emily M Schmidt

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Frank Heuts

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Lukasz Wardzinski

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Rupert Kenefeck

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Vitalijs Ovcinnikovs

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P2860

ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

ICOS co-stimulatory receptor is essential for T-cell activation and function

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

ICOS is critical for CD40-mediated antibody class switching

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524-529

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scholarly article

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10.1073/PNAS.1414576112

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2

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112

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2014-12-29T00:00:00Z

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270291355

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25548162

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4299196

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