Compensatory substitutions in the HIV-1 capsid reduce the fitness cost associated with resistance to a capsid-targeting small-molecule inhibitor.
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All-Atom Molecular Dynamics of Virus Capsids as Drug TargetsComposite Sequence-Structure Stability Models as Screening Tools for Identifying Vulnerable Targets for HIV Drug and Vaccine Development.Microplate-based assay for identifying small molecules that bind a specific intersubunit interface within the assembled HIV-1 capsid.HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease SeverityStructure and Glycan Binding of a New Cyanovirin-N Homolog.HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.Capsid-Dependent Host Factors in HIV-1 Infection.Novel In Vitro Screening System Based on Differential Scanning Fluorimetry to Search for Small Molecules against the Disassembly or Assembly of HIV-1 Capsid Protein.Structure of FIV capsid C-terminal domain demonstrates lentiviral evasion of genetic fragility by coevolved substitutions.Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74.
P2860
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P2860
Compensatory substitutions in the HIV-1 capsid reduce the fitness cost associated with resistance to a capsid-targeting small-molecule inhibitor.
description
2014 nî lūn-bûn
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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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P2093
P2860
P356
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Compensatory substitutions in ...... ting small-molecule inhibitor.
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P2093
Christopher Aiken
Mallori J Burse
Scott L Butler
Vaibhav B Shah
Wade S Blair
P2860
P304
P356
10.1128/JVI.01411-14
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P577
2014-10-15T00:00:00Z