Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin G

Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin G

Item
http://www.wikidata.org/entity/Q34993048
Crystal structure and mutagenic analysis of GDOsp, a gentisate 1,2-dioxygenase fromSilicibacter PomeroyiA complete library of amino acid alterations at N304 in Streptomyces clavuligerus deacetoxycephalosporin C synthase elucidates the basis for enhanced penicillin analogue conversion.Directed evolution of Streptomyces clavuligerus deacetoxycephalosporin C synthase for enhancement of penicillin G expansion.Iterative combinatorial mutagenesis as an effective strategy for generation of deacetoxycephalosporin C synthase with improved activity toward penicillin G.Relevant double mutations in bioengineered Streptomyces clavuligerus deacetoxycephalosporin C synthase result in higher binding specificities which improve penicillin bioconversion.Family shuffling of expandase genes to enhance substrate specificity for penicillin G.Production of microbial secondary metabolites: regulation by the carbon source.Carbon source regulation of antibiotic production.Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins.Modified Deacetylcephalosporin C Synthase for the Biotransformation of Semisynthetic CephalosporinsDirected evolution of a non-heme-iron-dependent extradiol catechol dioxygenase: identification of mutants with intradiol oxidative cleavage activity.Roles of 2-oxoglutarate oxygenases and isopenicillin N synthase in β-lactam biosynthesis
P2860

Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin G

Item
http://www.wikidata.org/entity/Q34993048
description
2003 nî lūn-bûn
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2003 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Engineering Streptomyces clavu ...... n activity toward penicillin G
@ast
Engineering Streptomyces clavu ...... n activity toward penicillin G
@en
Engineering Streptomyces clavu ...... n activity toward penicillin G
@nl
type
label
Engineering Streptomyces clavu ...... n activity toward penicillin G
@ast
Engineering Streptomyces clavu ...... n activity toward penicillin G
@en
Engineering Streptomyces clavu ...... n activity toward penicillin G
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Engineering Streptomyces clavu ...... n activity toward penicillin G
@ast
Engineering Streptomyces clavu ...... n activity toward penicillin G
@en
Engineering Streptomyces clavu ...... n activity toward penicillin G
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Engineering Streptomyces clavu ...... n activity toward penicillin G
@en
P2093
P2860
P304
P31
P356
10.1128/AEM.69.4.2306-2312.2003
P407
P433
P478
P577
P698
P932