Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.
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Structure and function of biotin-dependent carboxylasesKnockdown of pyruvate carboxylase or fatty acid synthase lowers numerous lipids and glucose-stimulated insulin release in insulinoma cellsMitochondrial metabolism of pyruvate is essential for regulating glucose-stimulated insulin secretionIdentification of ATP synthase as a lipid peroxide protein adduct in pancreatic islets from humans with and without type 2 diabetes mellitus.Geniposide regulates glucose-stimulated insulin secretion possibly through controlling glucose metabolism in INS-1 cells.Characterization of phospholipids in insulin secretory granules and mitochondria in pancreatic beta cells and their changes with glucose stimulation.Glucokinase activation repairs defective bioenergetics of islets of Langerhans isolated from type 2 diabetics.Structural similarities and differences between the human and the mouse pancreas.Mass spectrometry analysis shows the biosynthetic pathways supported by pyruvate carboxylase in highly invasive breast cancer cells.Characterization of P4 ATPase Phospholipid Translocases (Flippases) in Human and Rat Pancreatic Beta Cells: THEIR GENE SILENCING INHIBITS INSULIN SECRETIONRegulation of glucagon secretion in normal and diabetic human islets by γ-hydroxybutyrate and glycine.Knockdown of ATP citrate lyase in pancreatic beta cells does not inhibit insulin secretion or glucose flux and implicates the acetoacetate pathway in insulin secretionProteome analysis and conditional deletion of the EAAT2 glutamate transporter provide evidence against a role of EAAT2 in pancreatic insulin secretion in mice.High level of ATP citrate lyase expression in human and rat pancreatic isletsSingle-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetesEvidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?Minireview: intraislet regulation of insulin secretion in humans.Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.Regulatory role of adenosine in insulin secretion from pancreatic β-cells--action via adenosine A₁ receptor and beyond.Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.The Pancreatic β-Cell: A Bioenergetic Perspective.Fuel-Stimulated Insulin Secretion Depends upon Mitochondria Activation and the Integration of Mitochondrial and Cytosolic Substrate CyclesSerendipitous fragment-based drug discovery: ketogenic diet metabolites and statins effectively inhibit several carbonic anhydrases.Sex Differences in Androgen Regulation of Metabolism in Nonhuman Primates.Fibrin supports human fetal islet-epithelial cell differentiation via p70(s6k) and promotes vascular formation during transplantation.Pharmacological approach to understanding the control of insulin secretion in human islets.Nutrient sensing in pancreatic islets: lessons from congenital hyperinsulinism and monogenic diabetes.Influence of organ donor attributes and preparation characteristics on the dynamics of insulin secretion in isolated human islets.Intermittent hypoxia-induced epiregulin expression by IL-6 production in human coronary artery smooth muscle cells.Metformin Inhibits Mouse Islet Insulin Secretion and Alters Intracellular Calcium in a Concentration-Dependent and Duration-Dependent Manner near the Circulating Range.
P2860
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P2860
Differences between human and rodent pancreatic islets: low pyruvate carboxylase, atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Differences between human and ...... te in human pancreatic islets.
@ast
Differences between human and ...... te in human pancreatic islets.
@en
Differences between human and ...... te in human pancreatic islets.
@nl
type
label
Differences between human and ...... te in human pancreatic islets.
@ast
Differences between human and ...... te in human pancreatic islets.
@en
Differences between human and ...... te in human pancreatic islets.
@nl
prefLabel
Differences between human and ...... te in human pancreatic islets.
@ast
Differences between human and ...... te in human pancreatic islets.
@en
Differences between human and ...... te in human pancreatic islets.
@nl
P2093
P2860
P356
P1476
Differences between human and ...... te in human pancreatic islets.
@en
P2093
Ansaya Thonpho
Jon Odorico
Laura J Brown
Luis A Fernandez
Matthew S Hanson
Melissa J Longacre
Michael J MacDonald
Mindy Kendrick
Noaman M Hasan
Sarawut Jitrapakdee
P2860
P304
18383-18396
P356
10.1074/JBC.M111.241182
P407
P577
2011-03-22T00:00:00Z