Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents
about
γ-Tocotrienol as a Promising Countermeasure for Acute Radiation Syndrome: Current StatusDelayed hippocampal effects from a single exposure of prepubertal guinea pigs to sub-lethal dose of chlorpyrifos: a magnetic resonance imaging and spectroscopy studyRole of the calcium plateau in neuronal injury and behavioral morbidities following organophosphate intoxicationAnimal models that best reproduce the clinical manifestations of human intoxication with organophosphorus compoundsButyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behaviorDevelopment of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication(-)-Phenserine attenuates soman-induced neuropathologyMedical countermeasures for unwanted CBRN exposures: Part I chemical and biological threats with review of recent countermeasure patents.Zebrafish Models for Human Acute Organophosphorus PoisoningAn in vivo zebrafish screen identifies organophosphate antidotes with diverse mechanisms of actionPretreatment of Guinea pigs with galantamine prevents immediate and delayed effects of soman on inhibitory synaptic transmission in the hippocampus.Overcoming inhibitions.Medical Countermeasures for Radiation Exposure and Related Injuries: Characterization of Medicines, FDA-Approval Status and Inclusion into the Strategic National Stockpile.Catalytic bioscavengers against toxic esters, an alternative approach for prophylaxis and treatments of poisonings.Neuroprotection Against Diisopropylfluorophosphate in Acute Hippocampal Slices.Changing the Scale and Efficiency of Chemical Warfare Countermeasure Discovery Using the Zebrafish.Effectiveness of donepezil, rivastigmine, and (+/-)huperzine A in counteracting the acute toxicity of organophosphorus nerve agents: comparison with galantamineA novel approach to medical countermeasures against organophosphorus compound toxicityAnimal models for acute radiation syndrome drug discovery.Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase.Organophosphate-Hydrolyzing Enzymes as First-Line of Defence Against Nerve Agent-Poisoning: Perspectives and the Road Ahead.Differential binding of bispyridinium oxime drugs with acetylcholinesterase.Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain.Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases.A single in vivo application of cholinesterase inhibitors has neuron type-specific effects on nicotinic receptor activity in guinea pig hippocampus.Zebrafish is a predictive model for identifying compounds that protect against brain toxicity in severe acute organophosphorus intoxication.Treatment efficacy in a soman-poisoned guinea pig model: added value of physostigmine?Unbinding free energy of acetylcholinesterase bound oxime drugs along the gorge pathway from metadynamics-umbrella sampling investigation.Syrian gas attack reinforces need for better anti-sarin drugs.Acetylcholinesterase inhibition reveals endogenous nicotinic modulation of glutamate inputs to CA1 stratum radiatum interneurons in hippocampal slices.Galantamine prevents long-lasting suppression of excitatory synaptic transmission in CA1 pyramidal neurons of soman-challenged guinea pigs.Galantamine counteracts development of learning impairment in guinea pigs exposed to the organophosphorus poison soman: clinical significance.Neuroprotective Effects of Galantamine on Nerve Agent-Induced Neuroglial and Biochemical Changes.[+]-Huperzine A protects against soman toxicity in guinea pigs.Usefulness of administration of non-organophosphate cholinesterase inhibitors before acute exposure to organophosphates: assessment using paraoxon.Time Course, Behavioral Safety, and Protective Efficacy of Centrally Active Reversible Acetylcholinesterase Inhibitors in Cynomolgus Macaques.Development and clinical study of submicronic-atropine sulphate respiratory fluid as a novel organophosphorous poisoning antidote.Reversible cholinesterase inhibitors as pre-treatment for exposure to organophosphates: assessment using azinphos-methyl.
P2860
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P2860
Effective countermeasure against poisoning by organophosphorus insecticides and nerve agents
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Effective countermeasure again ...... insecticides and nerve agents
@ast
Effective countermeasure again ...... insecticides and nerve agents
@en
Effective countermeasure again ...... insecticides and nerve agents
@nl
type
label
Effective countermeasure again ...... insecticides and nerve agents
@ast
Effective countermeasure again ...... insecticides and nerve agents
@en
Effective countermeasure again ...... insecticides and nerve agents
@nl
prefLabel
Effective countermeasure again ...... insecticides and nerve agents
@ast
Effective countermeasure again ...... insecticides and nerve agents
@en
Effective countermeasure again ...... insecticides and nerve agents
@nl
P2093
P2860
P356
P1476
Effective countermeasure again ...... insecticides and nerve agents
@en
P2093
Edna F R Pereira
Edson X Albuquerque
James A Romano
Maristela Oliveira
Michael Adler
Robert K Kan
Tracey A Hamilton
William P Fawcett
William R Randall
Yasco Aracava
P2860
P304
13220-13225
P356
10.1073/PNAS.0605370103
P407
P577
2006-08-16T00:00:00Z