Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis
about
Transcription factor TEAD2 is involved in neural tube closureTeratogen-induced alterations in microRNA-34, microRNA-125b and microRNA-155 expression: correlation with embryonic p53 genotype and limb phenotypeThe BMP antagonist Noggin promotes cranial and spinal neurulation by distinct mechanismsFunctional Insights into Chromatin Remodelling from Studies on CHARGE SyndromeOxidative stress, unfolded protein response, and apoptosis in developmental toxicityDivergent functions of murine Pax3 and Pax7 in limb muscle developmentOverlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals.Altered gene expression in rat cranial neural crest cells exposed to a teratogenic glucose concentration in vitro: paradoxical downregulation of antioxidative defense genesThe closely related transcription factors Sox4 and Sox11 function as survival factors during spinal cord developmentMouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tubeBmp2 is required for cephalic neural tube closure in the mousePDGFR-A is a therapeutic target in alveolar rhabdomyosarcoma.A multi-resource data integration approach: identification of candidate genes regulating cell proliferation during neocortical development.Networks and pathways in pigmentation, health, and disease.Oxidative stress during diabetic pregnancy disrupts cardiac neural crest migration and causes outflow tract defects.FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development.Pathologies associated with the p53 response.The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.Pax3 stimulates p53 ubiquitination and degradation independent of transcriptionMyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3Increased DNA methyltransferase 3b (Dnmt3b)-mediated CpG island methylation stimulated by oxidative stress inhibits expression of a gene required for neural tube and neural crest development in diabetic pregnancy.Necdin enhances myoblasts survival by facilitating the degradation of the mediator of apoptosis CCAR1/CARP1Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma.Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint.Use of a murine embryonic stem cell line that is sensitive to high glucose environment to model neural tube development in diabetic pregnancyMaternal diet modulates the risk for neural tube defects in a mouse model of diabetic pregnancyPrevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice.The importance of having your SOX on: role of SOX10 in the development of neural crest-derived melanocytes and glia.Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival.MicroRNA gene expression signatures in the developing neural tubeThe genetic basis of mammalian neurulation.Spotlight on spotted mice: a review of white spotting mouse mutants and associated human pigmentation disorders.Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formationHyperglycemia impairs left-right axis formation and thereby disturbs heart morphogenesis in mouse embryos.Human neural tube defects: developmental biology, epidemiology, and geneticsAdvances in understanding the molecular causes of diabetes-induced birth defects.Experimental mechanisms of diabetic embryopathy and strategies for developing therapeutic interventions.Effect of maternal Tp53 gene G412C polymorphism on neural tube defects: A study from North India
P2860
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P2860
Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis
description
2002 nî lūn-bûn
@nan
2002 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մարտին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Rescue of neural tube defects ...... development and tumorigenesis
@ast
Rescue of neural tube defects ...... development and tumorigenesis
@en
type
label
Rescue of neural tube defects ...... development and tumorigenesis
@ast
Rescue of neural tube defects ...... development and tumorigenesis
@en
prefLabel
Rescue of neural tube defects ...... development and tumorigenesis
@ast
Rescue of neural tube defects ...... development and tumorigenesis
@en
P2860
P356
P1433
P1476
Rescue of neural tube defects ...... development and tumorigenesis
@en
P2093
Lydie Pani
Melissa Horal
P2860
P304
P356
10.1101/GAD.969302
P577
2002-03-01T00:00:00Z