Recent development and SAR analysis of colchicine binding site inhibitors.

Recent development and SAR analysis of colchicine binding site inhibitors.

Item
http://www.wikidata.org/entity/Q35007340
Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties.Synthesis and antiproliferative activities of ottelione a analoguesDesign, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.Reviewing Colchicaceae alkaloids - perspectives of evolution on medicinal chemistry.Nanotube interactions with microtubules: implications for cancer medicine.Design, Synthesis, and in vitro and in vivo Evaluations of (Z)-3,4,5-Trimethoxystyrylbenzenesulfonamides/sulfonates as Highly Potent Tubulin Polymerization Inhibitors.Synthesis, molecular docking and biological evaluation of 1-phenylsulphonyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as novel potential tubulin assembling inhibitors.How to deal with low-resolution target structures: using SAR, ensemble docking, hydropathic analysis, and 3D-QSAR to definitively map the αβ-tubulin colchicine site.Synthesis and biological evaluation of truncated α-tubulin-binding pironetin analogues lacking alkyl pendants in the side chain or the dihydropyrone ring.Pyrrole-Based Antitubulin Agents: Two Distinct Binding Modalities are Predicted for C-2 Analogs in the Colchicine Site.Developing novel C-4 analogues of pyrrole-based antitubulin agents: weak but critical hydrogen bonding in the colchicine site.Synthesis, Biological Evaluation, and Autophagy Mechanism of 12N-Substituted Sophoridinamines as Novel Anticancer Agents.Synthesis and biological evaluation of simplified pironetin analogues with modifications in the side chain and the lactone ring.Synthesis and biological evaluation of novel 5-chloro--(4-sulfamoylbenzyl) salicylamide derivatives as tubulin polymerization inhibitors
P2860

Recent development and SAR analysis of colchicine binding site inhibitors.

Item
http://www.wikidata.org/entity/Q35007340
description
2009 nî lūn-bûn
@nan
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Recent development and SAR analysis of colchicine binding site inhibitors.
@ast
Recent development and SAR analysis of colchicine binding site inhibitors.
@en
type
label
Recent development and SAR analysis of colchicine binding site inhibitors.
@ast
Recent development and SAR analysis of colchicine binding site inhibitors.
@en
prefLabel
Recent development and SAR analysis of colchicine binding site inhibitors.
@ast
Recent development and SAR analysis of colchicine binding site inhibitors.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Recent development and SAR analysis of colchicine binding site inhibitors.
@en
P2093
P304
P31
P356
10.2174/138955709789055234
P433
P478
P577
P698