Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. - Test2 - elhamkhani - TriplyDB

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.

http://www.wikidata.org/entity/Q35015993

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Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption Modulation of the rat hepatic cytochrome P4501A subfamily using biotin supplementation Effects of resveratrol on drug- and carcinogen-metabolizing enzymes, implications for cancer prevention.Computational and in vitro studies on the inhibitory effects of herbal compounds on human cytochrome P450 1A2.Up-regulation on cytochromes P450 in rat mediated by total alkaloid extract from Corydalis yanhusuo Effects of tobacco smoking and nicotine on cancer treatment.Inhibition of cytochrome p450 enzymes by the e- and z-isomers of norendoxifen.Cytochrome P450 family 1 inhibitors and structure-activity relationships.Cytochrome P450 enzyme mediated herbal drug interactions (Part 1)Dose-response of berberine on hepatic cytochromes P450 mRNA expression and activities in mice Caffeine Cytochrome P450 1A2 Metabolic Phenotype Does Not Predict the Metabolism of Heterocyclic Aromatic Amines in Humans.The Impact of CYP1A2 and CYP2E1 Genes Polymorphism on Theophylline Response Top Three Pharmacogenomics and Personalized Medicine Applications at the Nexus of Renal Pathophysiology and Cardiovascular Medicine.Subacute nicotine co-exposure has no effect on 2,2',3,5',6- pentachlorobiphenyl disposition but alters hepatic cytochrome P450 expression in the male rat.Evaluation of Oxidative Stress Response Related Genetic Variants, Pro-oxidants, Antioxidants and Prostate Cancer.Development and Comparison of Warfarin Dosing Algorithms in Stroke Patients Chronic administration of caderofloxacin, a new fluoroquinolone, increases hepatic CYP2E1 expression and activity in rats Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa.Identification of key licorice constituents which interact with cytochrome P450: evaluation by LC/MS/MS cocktail assay and metabolic profiling.Development of a Physiologically Based Pharmacokinetic Model to Predict Disease-Mediated Therapeutic Protein-Drug Interactions: Modulation of Multiple Cytochrome P450 Enzymes by Interleukin-6.Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective.Haematological toxicity of clozapine and some other drugs used in psychiatry.Perspectives on epigenetics and its relevance to adverse drug reactions.The effect and clinical consequences of hypoxia on cytochrome P450, membrane carrier proteins activity and expression.Substrate selectivity of drug-metabolizing cytochrome P450s predicted from crystal structures and in silico modeling.Acetylcholinesterase inhibitors: a patent review (2008 - present).Gene-environment interactions of selected pharmacogenes in arterial hypertension.Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics.Anti-Parkinson's disease drugs and pharmacogenetic considerations.Cigarette smoking and clopidogrel interaction.Biotransformation of xenobiotics in the human colon and rectum and its association with colorectal cancer.Modeling of interactions between xenobiotics and cytochrome P450 (CYP) enzymes.Pharmacokinetic Drug Interactions with Tobacco, Cannabinoids and Smoking Cessation Products.Flavonoids and Naphthoflavonoids: Wider Roles in the Modulation of Cytochrome P450 Family 1 Enzymes.Review of Ligand Specificity Factors for CYP1A Subfamily Enzymes from Molecular Modeling Studies Reported to-Date.Association between CYP1A2 gene single nucleotide polymorphisms and clinical responses to clozapine in patients with treatment-resistant schizophrenia.Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor.Mechanisms and Consequences of Drug-Drug Interactions.Erectile Dysfunction Drugs Changed the Protein Expressions and Activities of Drug-Metabolising Enzymes in the Liver of Male Rats.Fusing Sensor Paradigms to Acquire Chemical Information: An Integrative Role for Smart Biopolymeric Hydrogels.

P2860

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P2860

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2.

http://www.wikidata.org/entity/Q35015993

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2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies

Benzo(a)pyrene-caused increased G(1)-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts

Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2

Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2

Crystal structure of human cytochrome P450 2D6

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1

The relative contribution of human cytochrome P450 isoforms to the four caffeine oxidation pathways: an in vitro comparative study with cDNA-expressed P450s including CYP2C isoforms

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

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