Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness
about
TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cellsJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsEffect of Cigarette Smoking on Epithelial to Mesenchymal Transition (EMT) in Lung CancerMitogen-activated protein kinase signaling pathway and invasion and metastasis of gastric cancerThe emerging role of Twist proteins in hematopoietic cells and hematological malignanciesNormal and disease-related biological functions of Twist1 and underlying molecular mechanismsMolecular mechanisms of epithelial-mesenchymal transitionAKT-ions with a TWIST between EMT and METTackling Cancer Stem Cells via Inhibition of EMT Transcription FactorsThymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transitionTwist: a molecular target in cancer therapeuticsP130cas is required for TGF-β1-mediated epithelial-mesenchymal transition in lung cancerNID1, a new regulator of EMT required for metastasis and chemoresistance of ovarian cancer cellsCalmodulin promotes matrix metalloproteinase 9 production and cell migration by inhibiting the ubiquitination and degradation of TBC1D3 oncoprotein in human breast cancer cells.De-SUMOylation of FOXC2 by SENP3 promotes the epithelial-mesenchymal transition in gastric cancer cells.Multilayer control of the EMT master regulators.MAPK11 in breast cancer cells enhances osteoclastogenesis and bone resorption.Sox2 suppresses the invasiveness of breast cancer cells via a mechanism that is dependent on Twist1 and the status of Sox2 transcription activity.Structure-function studies of the bHLH phosphorylation domain of TWIST1 in prostate cancer cellsTamoxifen inhibits ER-negative breast cancer cell invasion and metastasis by accelerating Twist1 degradation.KITENIN promotes glioma invasiveness and progression, associated with the induction of EMT and stemness markers.Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation.Quercetin Suppresses Twist to Induce Apoptosis in MCF-7 Breast Cancer CellsThe function of steroid receptor coactivator-1 in normal tissues and cancerTWIST represses estrogen receptor-alpha expression by recruiting the NuRD protein complex in breast cancer cells.PRMT1 Is a Novel Regulator of Epithelial-Mesenchymal-Transition in Non-small Cell Lung Cancer.The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein DegradationEGFR Signal-Network Reconstruction Demonstrates Metabolic Crosstalk in EMT.MACC-1 Promotes Endothelium-Dependent Angiogenesis in Gastric Cancer by Activating TWIST1/VEGF-A Signal Pathway.Negative Regulatory Role of TWIST1 on SNAIL Gene Expression.Regulation of the protein stability of EMT transcription factorsSignaling pathway cooperation in TGF-β-induced epithelial-mesenchymal transition.Twist1 regulates keratinocyte proliferation and skin tumor promotion.DLX4 upregulates TWIST and enhances tumor migration, invasion and metastasisThe ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.EZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasisOverexpression of Lon contributes to survival and aggressive phenotype of cancer cells through mitochondrial complex I-mediated generation of reactive oxygen species.Epithelial-mesenchymal transition in breast cancer progression and metastasis.Preventing p38 MAPK-mediated MafA degradation ameliorates β-cell dysfunction under oxidative stress.
P2860
Q24594566-281094E9-FEF9-4C57-9766-1FCE8401C7BDQ26741279-5CFC8281-B992-42F7-82F4-1723AE19AB31Q26748357-5B7B6474-7579-4ED3-9BFC-8C15A778C0C3Q26778022-E2C4DC56-2FA0-4A32-B894-732F56D2A6CAQ26822434-FB1AE095-1C53-4AB0-B95B-7BC504B0E8B5Q26824524-0522F366-AA8A-4CA9-B58E-84023709A17EQ27013743-37E69233-9B02-49E4-A0FA-8E83ADBE7D0EQ28078987-87F4D9B5-BD68-43A2-9F20-5C8E843C3976Q28079863-C1F1E5DE-7A03-4BA3-9ADD-9FB277F56464Q28262567-AAF74397-25B4-4F5F-9250-9AABAFBE8BDBQ28294941-59D0A0FB-8CF3-48CE-95D3-2FC383E07C61Q33778346-742196BD-AE19-4565-BCA1-A11522D597FAQ33779379-F402865C-BC69-492F-A721-BF294BF18A33Q33829502-23D3ED9B-2B55-4F0D-9D0A-2B1ABDE21EAAQ34334509-6C187DBD-CFEA-43F6-BBFA-94AF51FB2A66Q34340552-37EA6A29-0382-4CC2-B21A-0D7BBFF91B89Q34602557-964B7707-33C6-43C7-BDFA-00B6A55B1295Q34788271-3F696EDD-4730-4DD5-8DEF-24F61C2E6B26Q35024079-AC6DFA68-07EA-475B-9B4D-285FC9B7FDE7Q35451620-CFB84B4C-17F4-47E0-9875-2BADE4DE31F7Q35550219-77AE2F44-A983-48A4-B13B-C8A7362F20A3Q35752136-4152BA31-908C-4439-BD61-B9CAFE804D2FQ35817167-A9849FD6-AF91-466A-ACAE-9141CB5BC047Q35828548-E3775301-B25C-45F5-9DB4-D3ADE9E47E6BQ35857237-0CC60159-79BA-4A5B-8A8D-F2A9E5A2B881Q35861015-7D2C6F4C-90EE-4872-8A12-3D9A8265DFE4Q35956614-85119D00-65E7-46EE-917E-818414915508Q36037821-C276F00D-BE45-4EA0-B89D-8152EFAC0E7DQ36046327-06ACB49A-3175-4527-BE81-35FDE082D0D0Q36082862-3D7A3E74-A210-489B-83FD-1E0F690C8078Q36124788-E7170931-1592-4685-A4C1-1F029FD23077Q36311752-2F1EB858-B1E0-4000-9A33-8B4C462BCF35Q36326865-9FFE847F-2319-466D-AE0D-755064883BB1Q36337130-FB824D8D-E59C-4F75-A09A-8C3DD50A7739Q36799312-CA448544-62D3-481C-A66B-5099BFC81EFEQ36862768-846D75BE-DB3E-4200-BE42-4A0A12860734Q36950009-0B8B7663-7250-4970-BD80-A340A45F3AF6Q36985078-8821ADBA-B4FC-4CD6-BBF2-A31C22547428Q36986452-94D6DD2F-8DF5-485F-B5C7-C8C01CBDA344Q36998047-90117D4B-E03D-4844-B19D-505626BCA354
P2860
Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@ast
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@en
type
label
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@ast
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@en
prefLabel
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@ast
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@en
P2093
P2860
P1433
P1476
Phosphorylation of serine 68 o ...... reast cancer cell invasiveness
@en
P2093
Jianming Xu
Junjiang Fu
P2860
P304
P356
10.1158/0008-5472.CAN-10-2914
P407
P577
2011-04-18T00:00:00Z