Possible formation of mitochondrial-RNA containing chimeric or trimeric RNA implies a post-transcriptional and post-splicing mechanism for RNA fusion
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To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAsHypothesis: Artifacts, Including Spurious Chimeric RNAs with a Short Homologous Sequence, Caused by Consecutive Reverse Transcriptions and Endogenous Random PrimersThe other side of the coin: the tumor-suppressive aspect of oncogenes and the oncogenic aspect of tumor-suppressive genes, such as those along the CCND-CDK4/6-RB axisUnbiased Mitoproteome Analyses Confirm Non-canonical RNA, Expanded Codon TranslationsIt Is Imperative to Establish a Pellucid Definition of Chimeric RNA and to Clear Up a Lot of Confusion in the Relevant Research.Two RNAs or DNAs May Artificially Fuse Together at a Short Homologous Sequence (SHS) during Reverse Transcription or Polymerase Chain Reactions, and Thus Reporting an SHS-Containing Chimeric RNA Requires Extra Caution.Chimeric mitochondrial peptides from contiguous regular and swinger RNA.Targeting antisense mitochondrial ncRNAs inhibits murine melanoma tumor growth and metastasis through reduction in survival and invasion factorsHow long noncoding RNAs enforce their will on mitochondrial activity: regulation of mitochondrial respiration, reactive oxygen species production, apoptosis, and metabolic reprogramming in cancer.Sharp switches between regular and swinger mitochondrial replication: 16S rDNA systematically exchanging nucleotides A<->T+C<->G in the mitogenome of Kamimuria wangi.Transcriptional-Readthrough RNAs Reflect the Phenomenon of "A Gene Contains Gene(s)" or "Gene(s) within a Gene" in the Human Genome, and Thus Are Not Chimeric RNAs.While it is not deliberate, much of today's biomedical research contains logical and technical flaws, showing a need for corrective action.
P2860
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P2860
Possible formation of mitochondrial-RNA containing chimeric or trimeric RNA implies a post-transcriptional and post-splicing mechanism for RNA fusion
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Possible formation of mitochon ...... icing mechanism for RNA fusion
@ast
Possible formation of mitochon ...... icing mechanism for RNA fusion
@en
type
label
Possible formation of mitochon ...... icing mechanism for RNA fusion
@ast
Possible formation of mitochon ...... icing mechanism for RNA fusion
@en
prefLabel
Possible formation of mitochon ...... icing mechanism for RNA fusion
@ast
Possible formation of mitochon ...... icing mechanism for RNA fusion
@en
P2093
P2860
P1433
P1476
Possible formation of mitochon ...... icing mechanism for RNA fusion
@en
P2093
An-ding Bi
D Joshua Liao
Emily Pauline Holman
Emily Weiss
Gung-wei Chirn
Hai-hong Shen
Jian-hua Zhou
Jian-min Wu
Yong-chang Ou-Yang
P2860
P304
P356
10.1371/JOURNAL.PONE.0077016
P407
P577
2013-10-24T00:00:00Z