Cabozantinib inhibits growth of androgen-sensitive and castration-resistant prostate cancer and affects bone remodeling
about
Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancersA phase I study of cabozantinib (XL184) in patients with differentiated thyroid cancer.A phase II study of GW786034 (pazopanib) with or without bicalutamide in patients with castration-resistant prostate cancerCharacterization of HGF/Met Signaling in Cell Lines Derived From Urothelial Carcinoma of the BladderThe biology of castration-resistant prostate cancerCabozantinib in chemotherapy-pretreated metastatic castration-resistant prostate cancer: results of a phase II nonrandomized expansion study.Prostate changes related to therapy: with special reference to hormone therapy.Cabozantinib resolves bone scans in tumor-naïve mice harboring skeletal injuries.Rapid modification of the bone microenvironment following short-term treatment with Cabozantinib in vivo.Current role of cabozantinib in metastatic castration-resistant prostate cancer.A phase I study of cabozantinib (XL184) in patients with renal cell cancer.Cabozantinib for the treatment of kidney cancer.Targeting Met and VEGFR Axis in Metastatic Castration-Resistant Prostate Cancer: 'Game Over'?Cabozantinib for Renal Cell Carcinoma: Current and Future Paradigms.Cabozantinib in genitourinary malignancies.C-Met/miR-130b axis as novel mechanism and biomarker for castration resistance state acquisition.Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts.Effective combinatorial immunotherapy for castration-resistant prostate cancerCabozantinib targets bone microenvironment modulating human osteoclast and osteoblast functions.LuCaP Prostate Cancer Patient-Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an--d Serve as Models for Evaluating Cancer Therapeutics.Cabozantinib-induced osteoblast secretome promotes survival and migration of metastatic prostate cancer cells in bone.BIGH3 Promotes Osteolytic Lesions in Renal Cell Carcinoma Bone Metastasis by Inhibiting Osteoblast Differentiation.Bone-Targeted Therapies in Cancer-Induced Bone Disease.Specific bone region localization of osteolytic versus osteoblastic lesions in a patient-derived xenograft model of bone metastatic prostate cancer.
P2860
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P2860
Cabozantinib inhibits growth of androgen-sensitive and castration-resistant prostate cancer and affects bone remodeling
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@ast
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@en
type
label
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@ast
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@en
prefLabel
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@ast
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@en
P2093
P2860
P1433
P1476
Cabozantinib inhibits growth o ...... er and affects bone remodeling
@en
P2093
Colm Morrissey
Dana T Aftab
Frauke Schimmoller
Holly M Nguyen
Lisha G Brown
Nazanin Ruppender
Robert L Vessella
Roman Gulati
Ted S Gross
P2860
P304
P356
10.1371/JOURNAL.PONE.0078881
P407
P577
2013-10-25T00:00:00Z