Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene
about
APOE genotype and stress response - a mini reviewCommon defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploringProteolytic cleavage of apolipoprotein E4 as the keystone for the heightened risk associated with Alzheimer's diseaseUshering in the study and treatment of preclinical Alzheimer diseaseEntorhinal cortical defects in Tg2576 mice are present as early as 2-4 months of age.Triad of Risk for Late Onset Alzheimer's: Mitochondrial Haplotype, APOE Genotype and Chromosomal SexBiochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's diseaseA defect in the mitochondrial complex III, but not complex IV, triggers early ROS-dependent damage in defined brain regions.A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's diseaseApoE4 induces Aβ42, tau, and neuronal pathology in the hippocampus of young targeted replacement apoE4 mice.Neuroprotective Effects of Icariin on Brain Metabolism, Mitochondrial Functions, and Cognition in Triple-Transgenic Alzheimer's Disease Mice.Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients.Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease.Estrogen: a master regulator of bioenergetic systems in the brain and bodyLow-level light therapy of the eye and brainWhite matter microstructure in late middle-age: Effects of apolipoprotein E4 and parental family history of Alzheimer's diseaseThe Alzheimer's disease mitochondrial cascade hypothesisAssociation of hypometabolism and amyloid levels in aging, normal subjectsIs Alzheimer's disease a systemic disease?APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease.Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.Characterizing the preclinical stages of Alzheimer's disease and the prospect of presymptomatic intervention.Identification of altered metabolic pathways in plasma and CSF in mild cognitive impairment and Alzheimer's disease using metabolomics.The Broad Impact of TOM40 on Neurodegenerative Diseases in AgingLifespan brain activity, β-amyloid, and Alzheimer's disease.Brain aging, Alzheimer's disease, and mitochondria.Different mechanisms of apolipoprotein E isoform-dependent modulation of prostaglandin E2 production and triggering receptor expressed on myeloid cells 2 (TREM2) expression after innate immune activation of microglia.A combined effect of two Alzheimer's risk genes on medial temporal activity during executive attention in young adults.Childhood Learning Disabilities and Atypical Dementia: A Retrospective Chart ReviewAPOE modifies the association between Aβ load and cognition in cognitively normal older adults.Reduced mitochondria cytochrome oxidase activity in adult children of mothers with Alzheimer's disease.Amyloid-Related Memory Decline in Preclinical Alzheimer's Disease Is Dependent on APOE ε4 and Is Detectable over 18-Months.Demographic and Lifestyle Characteristics, but Not Apolipoprotein E Genotype, Are Associated with Intelligence among Young Chinese College Students.Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.Amyloid and metabolic positron emission tomography imaging of cognitively normal adults with Alzheimer's parentsThe association between a polygenic Alzheimer score and cortical thickness in clinically normal subjects.Longitudinal modeling of cognitive aging and the TOMM40 effect.Early Life Epidemiology of Alzheimer's Disease--A Critical ReviewApolipoprotein E, not fibrillar β-amyloid, reduces cerebral glucose metabolism in normal aging.
P2860
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P2860
Reduced posterior cingulate mitochondrial activity in expired young adult carriers of the APOE ε4 allele, the major late-onset Alzheimer's susceptibility gene
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@ast
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@en
type
label
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@ast
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@en
prefLabel
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@ast
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@en
P2093
P2860
P356
P1476
Reduced posterior cingulate mi ...... lzheimer's susceptibility gene
@en
P2093
Alex E Roher
Andrew B Wolf
Jason J Corneveaux
Matthew J Huentelman
Richard J Caselli
Yael Kusne
P2860
P304
P356
10.3233/JAD-2010-100129
P577
2010-01-01T00:00:00Z