Anthrax lethal toxin induces endothelial barrier dysfunction
about
Gram-positive and gram-negative bacterial toxins in sepsis: a brief reviewAnthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctionsAcceleration of epithelial cell syndecan-1 shedding by anthrax hemolytic virulence factors.Anthrax Toxins in Context of Bacillus anthracis Spores and Spore GerminationCytoskeleton as an emerging target of anthrax toxinsCellular and physiological effects of anthrax exotoxin and its relevance to disease.The potential contributions of lethal and edema toxins to the pathogenesis of anthrax associated shockLung epithelial injury by B. anthracis lethal toxin is caused by MKK-dependent loss of cytoskeletal integrityIron and zinc exploitation during bacterial pathogenesisLethal and edema toxins in the pathogenesis of Bacillus anthracis septic shock: implications for therapyAsymmetric dimethylarginine levels in patients with cutaneous anthrax: a laboratory analysisThe effects of anthrax lethal toxin on host barrier functionAnthrax lethal toxin disrupts intestinal barrier function and causes systemic infections with enteric bacteriaBacillus anthracis has two independent bottlenecks that are dependent on the portal of entry in an intranasal model of inhalational infection.Updating perspectives on the initiation of Bacillus anthracis growth and dissemination through its host.Identification of novel non-hydroxamate anthrax toxin lethal factor inhibitors by topomeric searching, docking and scoring, and in vitro screening.Anthrax lethal toxin induces cell death-independent permeability in zebrafish vasculatureInjection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability.Assessment of alterations in barrier functionality and induction of proinflammatory and cytotoxic effects after sulfur mustard exposure of an in vitro coculture model of the human alveolo-capillary barrier.Role of N-terminal amino acids in the potency of anthrax lethal factor.Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy.The heart is an early target of anthrax lethal toxin in mice: a protective role for neuronal nitric oxide synthase (nNOS).Perturbation of mouse retinal vascular morphogenesis by anthrax lethal toxin.Inhibition of tumor angiogenesis by the matrix metalloproteinase-activated anthrax lethal toxin in an orthotopic model of anaplastic thyroid carcinoma.Key tissue targets responsible for anthrax-toxin-induced lethality.Bacillus anthracis protease InhA increases blood-brain barrier permeability and contributes to cerebral hemorrhages.Anthrax lethal toxin induces acute diastolic dysfunction in rats through disruption of the phospholamban signaling networkPathophysiological manifestations in mice exposed to anthrax lethal toxin.Development of a comprehensive, validated pharmacophore hypothesis for anthrax toxin lethal factor (LF) inhibitors using genetic algorithms, Pareto scoring, and structural biology.Influenza infects lung microvascular endothelium leading to microvascular leak: role of apoptosis and claudin-5.MyD88-dependent signaling protects against anthrax lethal toxin-induced impairment of intestinal barrier function.Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice.Anthrax lethal toxin disrupts the endothelial permeability barrier through blocking p38 signaling.Anthrax lethal and edema toxins produce different patterns of cardiovascular and renal dysfunction and synergistically decrease survival in caninesTargeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapyMolecular determinants for a cardiovascular collapse in anthraxConsequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.Contribution of lethal toxin and edema toxin to the pathogenesis of anthrax meningitis.Anthrax lethal toxin-induced gene expression changes in mouse lung.Anthrax lethal toxin-mediated disruption of endothelial VE-cadherin is attenuated by inhibition of the Rho-associated kinase pathway
P2860
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P2860
Anthrax lethal toxin induces endothelial barrier dysfunction
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Anthrax lethal toxin induces endothelial barrier dysfunction
@ast
Anthrax lethal toxin induces endothelial barrier dysfunction
@en
type
label
Anthrax lethal toxin induces endothelial barrier dysfunction
@ast
Anthrax lethal toxin induces endothelial barrier dysfunction
@en
prefLabel
Anthrax lethal toxin induces endothelial barrier dysfunction
@ast
Anthrax lethal toxin induces endothelial barrier dysfunction
@en
P2093
P2860
P1476
Anthrax lethal toxin induces endothelial barrier dysfunction
@en
P2093
Amber D Steele
Felice D'Agnillo
Jason M Warfel
P2860
P304
P356
10.1016/S0002-9440(10)62496-0
P407
P577
2005-06-01T00:00:00Z