Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
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Gut dysfunction in Parkinson's diseaseGut Feelings About α-Synuclein in Gastrointestinal Biopsies: Biomarker in the Making?The bowel and beyond: the enteric nervous system in neurological disordersEnteric neurons from Parkinson's disease patients display ex vivo aberrations in mitochondrial structure.Structure, Distribution, and Genetic Profile of α-Synuclein and Their Potential Clinical Application in Parkinson's Disease.Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies.Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson's Disease.Enteric nervous system α-synuclein immunoreactivity in idiopathic REM sleep behavior disorder.Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy FindingsEvaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies.Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects.Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients.Targeting α-synuclein as a therapeutic strategy for Parkinson's disease.Recognition and treatment of autonomic disturbances in Parkinson's disease.The relevance of pre-motor symptoms in Parkinson's disease.The Concept of Prodromal Parkinson's Disease.Review: Parkinson's disease: from synaptic loss to connectome dysfunction.What a gastrointestinal biopsy can tell us about Parkinson's disease?Biomarkers in Prodromal Parkinson Disease: a Qualitative Review.How strong is the evidence that Parkinson's disease is a prion disorder?Alpha-synuclein in gastric and colonic mucosa in Parkinson's disease: Limited role as a biomarker.The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease.Precision medicine for disease modification in Parkinson disease.Alpha-Synuclein to the Rescue: Immune Cell Recruitment by Alpha-Synuclein during Gastrointestinal Infection.Animal models of α-synucleinopathy for Parkinson disease drug development.Distinct pattern of enteric phospho-alpha-synuclein aggregates and gene expression profiles in patients with Parkinson's diseaseRotenone and elevated extracellular potassium concentration induce cell-specific fibrillation of α-synuclein in axons of cholinergic enteric neurons in the guinea-pig ileum.Downregulation of neuronal vasoactive intestinal polypeptide in Parkinson's disease and chronic constipation.Does Parkinson's disease start in the gut?Chronic constipation: improved understanding offers a new therapeutic approach.How does parkinson's disease begin? Perspectives on neuroanatomical pathways, prions, and histology.α-Synuclein in the colon and premotor markers of Parkinson disease in neurologically normal subjects.Peripheral synuclein tissue markers: a step closer to Parkinson's disease diagnosis.The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease.Similar α-Synuclein staining in the colon mucosa in patients with Parkinson's disease and controls.Response of colonic motility to dopaminergic stimulation is subverted in rats with nigrostriatal lesion: relevance to gastrointestinal dysfunctions in Parkinson's disease.Optimizing Western Blots for the Detection of Endogenous α-Synuclein in the Enteric Nervous System.Relation of Enteric α-Synuclein to Gastrointestinal Dysfunction in Patients With Parkinson's Disease and in Neurologically Intact SubjectsParkinson's Disease Biomarkers: Where Are We and Where Do We Go Next?
P2860
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P2860
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
description
2015 nî lūn-bûn
@nan
2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@ast
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@en
type
label
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@ast
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@en
prefLabel
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@ast
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@en
P2093
P2860
P921
P1433
P1476
Colonic mucosal a-synuclein lacks specificity as a biomarker for Parkinson disease.
@en
P2093
Amaal Al Dakheel
Andrew Gao
Drew S Kern
Lili-Naz Hazrati
Louis W C Liu
Naomi P Visanji
P2860
P304
P356
10.1212/WNL.0000000000001240
P407
P577
2015-02-01T00:00:00Z