Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine.

Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine.

Item
http://www.wikidata.org/entity/Q35107603
Characterization of pertussis toxin analogs containing mutations in B-oligomer subunitsIdentification of B-cell epitopes on the S4 subunit of pertussis toxinThe family of bacterial ADP-ribosylating exotoxinsStable expression of pertussis toxin in Bordetella bronchiseptica under the control of a tightly regulated promoter.Neutralizing antibodies and immunoprotection against pertussis and tetanus obtained by use of a recombinant pertussis toxin-tetanus toxin fusion protein.Construction of Bordetella pertussis strains with enhanced production of genetically-inactivated Pertussis Toxin and Pertactin by unmarked allelic exchange.Site-specific alterations in the B oligomer that affect receptor-binding activities and mitogenicity of pertussis toxin.Identification of T- and B-cell epitopes of the S2 and S3 subunits of pertussis toxin by use of synthetic peptides.Construction of a diphtheria toxin A fragment-C180 peptide fusion protein which elicits a neutralizing antibody response against diphtheria toxin and pertussis toxin.Construction of minitransposons for constitutive and inducible expression of pertussis toxin in bvg-negative Bordetella bronchisepticaCharacterization of murine monoclonal antibodies that recognize defined epitopes of pertussis toxin and neutralize its toxic effect on Chinese hamster ovary cellsConfocal microscopy study of pertussis toxin and toxoids on CHO-cells.Mutations in the S1 subunit of pertussis toxin that affect secretionConstruction of Bordetella pertussis strains that overproduce genetically inactivated pertussis toxin
P2860

Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine.

Item
http://www.wikidata.org/entity/Q35107603
description
1990 nî lūn-bûn
@nan
1990 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
name
Engineering of genetically det ...... binant whooping cough vaccine.
@ast
Engineering of genetically det ...... binant whooping cough vaccine.
@en
type
label
Engineering of genetically det ...... binant whooping cough vaccine.
@ast
Engineering of genetically det ...... binant whooping cough vaccine.
@en
prefLabel
Engineering of genetically det ...... binant whooping cough vaccine.
@ast
Engineering of genetically det ...... binant whooping cough vaccine.
@en
P1433
P1476
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932
P1433
P1476
Engineering of genetically det ...... binant whooping cough vaccine.
@en
P2093
P2860
P304
P31
P407
P433
P478
P577
P698
P932