Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity.
about
A solvent-free thermosponge nanoparticle platform for efficient delivery of labile proteins.Design, modeling, expression, and chemoselective PEGylation of a new nanosize cysteine analog of erythropoietin.Improving the stability of the EC1 domain of E-cadherin by thiol alkylation of the cysteine residue.Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b.The role of thiols and disulfides on protein stability.Product development issues for PEGylated proteins.Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites.Evaluation of bioactivity and pharmacokinetic characteristics of PEGylated P.pastoris-expressed erythropoietin.Controlled concealment of exposed clearance and immunogenic domains by site-specific polyethylene glycol attachment to acetylcholinesterase hypolysine mutants.Human ubiquitin C promoter based expression of erythropoietin in CHO K1 cell lines: a simple transfectants screening approach.Identification of anchor points for chemical modification of a small cysteine-rich protein by using a cysteine scan.
P2860
Q34579897-6BA3C2F5-B3C7-4B4B-9BC2-028DAC4A99C0Q35090476-A12E6200-DD35-4A56-9000-E3D9647DE2F0Q35980733-D8532A9B-55DB-49F6-9AE8-76638F6981C9Q37404242-6345335C-D00F-4A5B-B768-53BDA7C56E99Q37524089-AE43D01D-58C8-4ED0-9360-BE0E53AEAE9BQ37790702-FD2BD21E-5E69-4AA7-AC6E-2B3DC672D483Q38802664-9DA19A1B-6480-47B6-A63E-26CE640F0B62Q39479432-5DF8BFF1-BF5E-4E79-9647-1FB10A237664Q40068841-1B0FD978-491C-45F9-8946-104F00B48338Q44987524-35E3AC36-488F-4A4D-AB7C-8D17475F93C2Q53407192-0CAA74D3-6DF0-40E8-8285-CA59119C9014
P2860
Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@ast
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@en
type
label
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@ast
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@en
prefLabel
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@ast
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@en
P2093
P2860
P1476
Design of homogeneous, monopeg ...... reserved in vitro bioactivity.
@en
P2093
Dana L Long
Daniel H Doherty
Darin J Smith
Dean P Edwards
Elizabeth A Chlipala
George N Cox
Kurt R Christensen
Mary S Rosendahl
Stephen P Eisenberg
P2860
P304
P356
10.1016/J.EXPHEM.2006.02.011
P577
2006-06-01T00:00:00Z