Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.
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Induction of resistance to azole drugs in Trypanosoma cruzi.Bromopyrrole alkaloids as lead compounds against protozoan parasitesTrypanocidal activity of marine natural productsStructure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenasePharmacological Characterization, Structural Studies, and In Vivo Activities of Anti-Chagas Disease Lead Compounds Derived from TipifarnibAntitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite GrowthComplexes of Trypanosoma cruzi Sterol 14 -Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease: STRUCTURAL BASIS FOR PATHOGEN SELECTIVITYAdenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug designIdentification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screeningIn vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compoundsThe susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposingActivity in vivo of anti-Trypanosoma cruzi compounds selected from a high throughput screeningAgrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas diseaseIdentification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaignBioactivity of fungal endophytes as a function of endophyte taxonomy and the taxonomy and distribution of their host plantsNatural terpenoids from Ambrosia species are active in vitro and in vivo against human pathogenic trypanosomatidsSynergy testing of FDA-approved drugs identifies potent drug combinations against Trypanosoma cruziHigh throughput screening for anti-Trypanosoma cruzi drug discoveryAutomated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell lineIdentification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sicknessNew compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.Inhibitory activity of marine sponge-derived natural products against parasitic protozoa.Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery.Methodological advances in drug discovery for Chagas disease.Dialkylimidazole inhibitors of Trypanosoma cruzi sterol 14α-demethylase as anti-Chagas disease agentsChemical constituents of the new endophytic fungus Mycosphaerella sp. nov. and their anti-parasitic activityPotent anti-Trypanosoma cruzi activities of oxidosqualene cyclase inhibitors.Detection of live Trypanosoma cruzi in tissues of infected mice by using histochemical stain for beta-galactosidase.Credneramides A and B: neuromodulatory phenethylamine and isopentylamine derivatives of a vinyl chloride-containing fatty acid from cf. Trichodesmium sp. nov.Acylation-dependent export of Trypanosoma cruzi phosphoinositide-specific phospholipase C to the outer surface of amastigotesIn vitro antiplasmodial, antileishmanial and antitrypanosomal activities of selected medicinal plants used in the traditional Arabian Peninsular region.High-content imaging for automated determination of host-cell infection rate by the intracellular parasite Trypanosoma cruzi.Tc52 amino-terminal-domain DNA carried by attenuated Salmonella enterica serovar Typhimurium induces protection against a Trypanosoma cruzi lethal challenge.Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine.2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage Plasmodium infections.A class of sterol 14-demethylase inhibitors as anti-Trypanosoma cruzi agents.Drug strategies targeting CYP51 in neglected tropical diseasesSelective inhibitors of methionyl-tRNA synthetase have potent activity against Trypanosoma brucei Infection in Mice
P2860
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P2860
Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.
description
1996 nî lūn-bûn
@nan
1996 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Efficient technique for screen ...... expressing beta-galactosidase.
@ast
Efficient technique for screen ...... expressing beta-galactosidase.
@en
type
label
Efficient technique for screen ...... expressing beta-galactosidase.
@ast
Efficient technique for screen ...... expressing beta-galactosidase.
@en
prefLabel
Efficient technique for screen ...... expressing beta-galactosidase.
@ast
Efficient technique for screen ...... expressing beta-galactosidase.
@en
P2093
P2860
P1476
Efficient technique for screen ...... expressing beta-galactosidase.
@en
P2093
A C La Flamme
C L Verlinde
F S Buckner
W C Van Voorhis
P2860
P304
P407
P577
1996-11-01T00:00:00Z