Genetic toxicology in the 21st century: reflections and future directions. - Test2 - elhamkhani - TriplyDB

Genetic toxicology in the 21st century: reflections and future directions.

Genetic toxicology in the 21st century: reflections and future directions.

http://www.wikidata.org/entity/Q35177174

about

Strategic applications of gene expression: from drug discovery/development to bedside Effect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cells Non-monotonic dose responses in studies of endocrine disrupting chemicals: bisphenol a as a case study Comparative and mechanistic genotoxicity assessment of nanomaterials via a quantitative toxicogenomics approach across multiple species.Toxicologic pathology in the 21st century.Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9.Adaptation of high-throughput screening in drug discovery-toxicological screening tests.Criteria for environmentally associated autoimmune diseases.The Comparative Toxicogenomics Database: update 2013.Incorporation of metabolic activation potentiates cyclophosphamide-induced DNA damage response in isogenic DT40 mutant cells Biological clues to potent DNA-damaging activities in food and flavoring.Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity.Systematic verification of upstream regulators of a computable cellular proliferation network model on non-diseased lung cells using a dedicated dataset.Advancing toxicology research using in vivo high throughput toxicology with small fish models.(Q)SAR modeling and safety assessment in regulatory review.Investigative safety science as a competitive advantage for Pharma.Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.Development of an in vitro PIG-A gene mutation assay in human cells.Ames Test to Detect Mutagenicity of 2-Alkylcyclobutanones: A Review.A high-fidelity method for genomic sequencing of single somatic cells reveals a very high mutational burden.Effectiveness of CASE Ultra Expert System in Evaluating Adverse Effects of Drugs.A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro Perspectives of the development strategies for a future toxicity testing system in China: challenges and opportunities.Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.The Impact of Novel Assessment Methodologies in Toxicology on Green Chemistry and Chemical Alternatives.Genotoxicity testing: progress and prospects for the next decade.The Transformics Assay: First Steps for the Development of an Integrated Approach to Investigate the Malignant Cell Transformation in vitro.Developing a genetic signature to predict drug response in ovarian cancer.

P2860

Q26864172-179903FE-E55A-4908-A8E5-FEC1C2A210BF Q28385533-D0FA2FFA-7A55-42BA-BCD5-AE41814543EB Q33676877-5A976454-00B2-4A70-BF0E-2D5269A70C24 Q34473335-26B25AE9-1A2F-4C84-9485-0111B47D1884 Q34473377-16C39F41-C6FA-4340-9491-E792ADA69259 Q35686057-BC84D85B-75D4-4EE5-80C8-8C434707DB42 Q35719340-5A3F5CDC-D75B-4432-9040-E0D72A7371FE Q36310013-8C8AABD5-DC62-4DB0-A3EB-9B6ECC672F23 Q36491395-4D0E7D3F-5590-4626-BA7C-C4C5B38819AF Q36492435-36B46270-0665-441A-8FFA-9FBFCEAFBB76 Q36717985-AAAD86C7-38B3-4817-B42A-6353431044D8 Q36749842-79825694-E2AC-4B0B-B02C-4CD98609588C Q37070705-6DB0CAF2-E2B5-4DD8-81BE-2CE0B14589D7 Q37610145-82673F7B-EDAE-40F9-89DD-B8B309D820C4 Q37976993-3B4A480F-6D0D-4382-8C45-B6639D66D4E3 Q38024403-B1244E2C-C12B-422E-8EDC-F42324A9E10F Q38454300-F29F6E69-5AF7-4095-9EB3-78FE0B8009C9 Q38722763-4E9FD991-4159-485A-9677-A92C0713B7EE Q39362151-6E33497F-4953-4F42-A1F5-58CA45455DC9 Q39454064-B5342F76-47ED-41E3-895B-DCDD418B0748 Q39536154-D4E6C434-F021-45B8-B0EC-F2D86A3489E1 Q41194750-EAF4C9E8-343E-4534-9ED1-153DEDA2A330 Q42586468-1BD27E20-5906-4A57-9742-7BE28F08D42B Q42707254-8228601E-9AB8-491B-8560-0A50553DCD18 Q49603968-8A2DCE3C-F6EE-460C-8170-D429B43A48E8 Q50180152-4FF551C7-937B-4382-B038-A0B2849D9CCF Q52648682-0122C730-650A-44D9-8B2C-A1B649341797 Q55028564-D5362B1C-987C-4E4F-9752-779FB31974A6

P2860

Genetic toxicology in the 21st century: reflections and future directions.

http://www.wikidata.org/entity/Q35177174

description

2011 nî lūn-bûn

@nan

2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Genetic toxicology in the 21st century: reflections and future directions.

@ast

Genetic toxicology in the 21st century: reflections and future directions.

@en

type

label

Genetic toxicology in the 21st century: reflections and future directions.

@ast

Genetic toxicology in the 21st century: reflections and future directions.

@en

prefLabel

Genetic toxicology in the 21st century: reflections and future directions.

@ast

Genetic toxicology in the 21st century: reflections and future directions.

@en

P1433

Q35177174-22DE5A4B-784E-460E-B21E-7C656543A1B0

P1476

Q35177174-B5E6B3C5-DD50-4770-9742-1C7D5987AB24

P2093

Q35177174-01C5EAD7-8033-4597-B216-26332B36BBAF

Q35177174-09CF672F-5182-4914-832C-7AEE8778EC1D

Q35177174-1CAC43A7-A3DC-4035-9F7D-854085996301

Q35177174-27AEFE6C-6750-4961-8DF5-F4FB76788811

Q35177174-996DCF2E-9F15-44CA-BD32-98EBA6D26ABD

Q35177174-A4C01173-5458-4FAC-AB28-A0672314B7B9

Q35177174-F8A166D0-EF5D-48DC-AA23-C20D02736970

P2860

Q35177174-00B6631D-49BF-4D1C-BECD-E61FA41F25D3

Q35177174-03D8837F-885F-4D11-9EE5-9ADAD62D604E

Q35177174-0A495798-D14E-432E-8410-5382FA3589BF

Q35177174-0B78E444-2442-4842-860C-97254F2EA2D3

Q35177174-1BD5411E-6148-4581-B484-5B8685DACA17

Q35177174-292B8C68-4D15-4F6B-A7AF-79D50E7D8C68

Q35177174-29C6E2C7-EEFC-4B9D-B965-EB1E24878A4A

Q35177174-29CA9D47-0B32-4E2F-B2E3-6CD9A82F73D8

Q35177174-2CBB6953-180F-4445-8344-61E588C779B0

Q35177174-32926B69-1688-4323-8B47-2F8FC1C8E8FE

P304

Q35177174-99E53715-514B-44D3-B5E6-FED41027BF2E

P31

Q35177174-EA993797-D184-4ECA-AF60-079E84A59595

P356

Q35177174-3BC0011F-023D-410E-9456-C682B3669834

P433

Q35177174-232F28B1-4951-4A3D-8558-8CFAE9294571

P478

Q35177174-5E1B8454-AF36-47E7-B626-5782F4DDAE3E

P577

Q35177174-68797E96-B701-43CB-B249-08C1CB7EC6A1

P5875

Q35177174-072F6249-C4F9-41A0-A5F0-7C7DDF8DAB32

P698

Q35177174-7D77F961-C74E-4F49-9089-6309444FE30E

P932

Q35177174-AF1521D9-C2AC-4281-ADE0-BF1370F99FA1

P356

P1433

Environmental and Molecular Mutagenesis

P1476

Genetic toxicology in the 21st century: reflections and future directions.

@en

P2093

Ann M Richard

http://www.w3.org/2001/XMLSchema#string

Brinda Mahadevan

http://www.w3.org/2001/XMLSchema#string

Michael D Waters

http://www.w3.org/2001/XMLSchema#string

R Daniel Benz

http://www.w3.org/2001/XMLSchema#string

Raymond A Kemper

http://www.w3.org/2001/XMLSchema#string

Raymond R Tice

http://www.w3.org/2001/XMLSchema#string

Ronald D Snyder

http://www.w3.org/2001/XMLSchema#string

P2860

A critical role for the ubiquitin-conjugating enzyme Ubc13 in initiating homologous recombination

CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals

Genetic toxicology data in the evaluation of potential human environmental carcinogens.

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: II. Identification of genotoxicants, reprotoxicants, and carcinogens using in silico methods.

An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints.

Derivation and validation of toxicophores for mutagenicity prediction.

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries.

Toxicological and clinical computational analysis and the US FDA/CDER.

P304

339-354

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/EM.20653

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

52

http://www.w3.org/2001/XMLSchema#string

P577

2011-04-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51094511

http://www.w3.org/2001/XMLSchema#string

P698

21538556

http://www.w3.org/2001/XMLSchema#string

P932

3160238

http://www.w3.org/2001/XMLSchema#string