K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
about
M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to NckGermline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotypeK-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and functionPaired-like homeoprotein ESXR1 acts as a sequence-specific transcriptional repressor of the human K-ras geneThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.A vascular gene trap screen defines RasGRP3 as an angiogenesis-regulated gene required for the endothelial response to phorbol estersDisruption of hyaluronan synthase-2 abrogates normal cardiac morphogenesis and hyaluronan-mediated transformation of epithelium to mesenchymeThe RASopathies: developmental syndromes of Ras/MAPK pathway dysregulationMoving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesThe Key Role of Calmodulin in KRAS-Driven AdenocarcinomasK-ras/PI3K-Akt signaling is essential for zebrafish hematopoiesis and angiogenesisA natural small molecule, catechol, induces c-Myc degradation by directly targeting ERK2 in lung cancerRas-induced cellular events (review)Structure and function of the C-terminal hypervariable region of K-Ras4B in plasma membrane targetting and transformationCalmodulin binds to K-Ras, but not to H- or N-Ras, and modulates its downstream signalingInsights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysisH-Ras and phosphoinositide 3-kinase cooperate to induce alpha(1,3)-fucosyltransferase VII expression in Jurkat T cellsGermline KRAS mutations cause Noonan syndromeLung epithelial branching program antagonizes alveolar differentiationGenetic interaction between Rb and K-ras in the control of differentiation and tumor suppressionDisruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cellsH-Ras signaling and K-Ras signaling are differentially dependent on endocytosis.Suprachiasmatic nucleus circadian oscillatory protein, a novel binding partner of K-Ras in the membrane rafts, negatively regulates MAPK pathwayRhes is involved in striatal functionInvolvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signalingGenetic analysis of Ras signalling pathways in cell proliferation, migration and survival.Lipophilic bisphosphonates plus rapamycin: a deadly combination for KRAS-mutated lung adenocarcinomaCharacteristics of lung cancers harboring NRAS mutationsRas oncogenes: split personalitiesMASL1 induces erythroid differentiation in human erythropoietin-dependent CD34+ cells through the Raf/MEK/ERK pathwayRas history: The saga continues.Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells.Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinaseThe pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.Analysis of k-ras nuclear expression in fibroblasts and mesangial cellsActivated Ras alters lens and corneal development through induction of distinct downstream targets.Ras membrane orientation and nanodomain localization generate isoform diversity
P2860
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P2860
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@ast
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@en
type
label
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@ast
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@en
prefLabel
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@ast
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@en
P2093
P2860
P356
P1433
P1476
K-ras is an essential gene in the mouse with partial functional overlap with N-ras.
@en
P2093
D Greenbaum
K Cichowski
R Kucherlapati
R T Bronson
P2860
P304
P356
10.1101/GAD.11.19.2468
P577
1997-10-01T00:00:00Z