SMOCs: supramolecular organizing centres that control innate immunity. - Test2 - elhamkhani - TriplyDB

SMOCs: supramolecular organizing centres that control innate immunity.

SMOCs: supramolecular organizing centres that control innate immunity.

http://www.wikidata.org/entity/Q35216106

about

As a toxin dies a prion comes to life: A tentative natural history of the [Het-s] prion Interferon-induced guanylate-binding proteins in inflammasome activation and host defense Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC Nuclear sensing of viral DNA, epigenetic regulation of herpes simplex virus infection, and innate immunity Bacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy.Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria.Zinc-Induced Polymerization of Killer-Cell Ig-like Receptor into Filaments Promotes Its Inhibitory Function at Cytotoxic Immunological Synapses.Supramolecular organizing centers (SMOCs) as signaling machines in innate immune activation.A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules.ASC filament formation serves as a signal amplification mechanism for inflammasomes The N-terminal loop of IRAK-4 death domain regulates ordered assembly of the Myddosome signalling scaffold.PRRs are watching you: Localization of innate sensing and signaling regulators.The hierarchical structural architecture of inflammasomes, supramolecular inflammatory machines.Early innate immune responses to bacterial LPS.Structural Mechanisms in NLR Inflammasome Assembly and Signaling.Animal NLRs provide structural insights into plant NLR function.Microbe-inducible trafficking pathways that control Toll-like receptor signaling.The Inflammatory Signal Adaptor RIPK3: Functions Beyond Necroptosis.Multi-receptor detection of individual bacterial products by the innate immune system.The Peroxisome-Mitochondria Connection: How and Why?Lipopolysaccharide Detection across the Kingdoms of Life.Innate Immune Receptors as Competitive Determinants of Cell Fate.CD14 is critical for TLR2-mediated M1 macrophage activation triggered by N-glycan recognition.A Single Bacterial Immune Evasion Strategy Dismantles Both MyD88 and TRIF Signaling Pathways Downstream of TLR4 AIM2 inflammasome activation and regulation: A structural perspective.How inflammasomes inform adaptive immunity.Type III IFNs Are Commonly Induced by Bacteria-Sensing TLRs and Reinforce Epithelial Barriers during Infection.Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling.The intra- and extracellular functions of ASC specks.The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages.Biochemical Isolation of the Myddosome from Murine Macrophages.Peptidoglycan-Sensing Receptors Trigger the Formation of Functional Amyloids of the Adaptor Protein Imd to Initiate Drosophila NF-κB Signaling.Activation of the Innate Immune Receptors: Guardians of the Micro Galaxy : Activation and Functions of the Innate Immune Receptors.A one-protein signaling pathway in the innate immune system.Dynamics of in vivo ASC speck formation.Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.Digital signaling network drives the assembly of the AIM2-ASC inflammasome.High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles.Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming.

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P2860

SMOCs: supramolecular organizing centres that control innate immunity.

http://www.wikidata.org/entity/Q35216106

description

2014 nî lūn-bûn

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2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

SMOCs: supramolecular organizing centres that control innate immunity.

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SMOCs: supramolecular organizing centres that control innate immunity.

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SMOCs: supramolecular organizing centres that control innate immunity.

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SMOCs: supramolecular organizing centres that control innate immunity.

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SMOCs: supramolecular organizing centres that control innate immunity.

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SMOCs: supramolecular organizing centres that control innate immunity.

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P1433

Nature Reviews Immunology

P1476

SMOCs: supramolecular organizing centres that control innate immunity.

@en

P2093

Hao Wu

http://www.w3.org/2001/XMLSchema#string

Jonathan C Kagan

http://www.w3.org/2001/XMLSchema#string

Venkat Giri Magupalli

http://www.w3.org/2001/XMLSchema#string

P2860

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis

The Fas-FADD death domain complex structure reveals the basis of DISC assembly and disease mutations

Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

Peroxisomes are signaling platforms for antiviral innate immunity

MAVS forms functional prion-like aggregates to activate and propagate antiviral innate immune response

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation

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821-826

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scholarly article

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10.1038/NRI3757

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12

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14

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2014-10-31T00:00:00Z

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25359439

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4373346

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