A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.
about
Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaeaNitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic PropertiesGene expression profiles of NO- and HNO-donor treated breast cancer cells: insights into tumor response and resistance pathwaysFifty years of diazeniumdiolate research. From laboratory curiosity to broad-spectrum biomedical advancesMn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathwaysSignaling and stress: The redox landscape in NOS2 biologyInhibition of tubulin polymerization by hypochlorous acid and chloraminesPhotoinduced release of nitroxyl and nitric oxide from diazeniumdiolatesReactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class.Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation propertiesNitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.Glutathione sulfinamide serves as a selective, endogenous biomarker for nitroxyl after exposure to therapeutic levels of donors.Analysis of the HNO and NO donating properties of alicyclic amine diazeniumdiolates.Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.HNO and NO release from a primary amine-based diazeniumdiolate as a function of pHThe chemistry of nitroxyl-releasing compounds.Rapid and selective nitroxyl (HNO) trapping by phosphines: kinetics and new aqueous ligations for HNO detection and quantitation.Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBS-QB3 calculationsChemotherapeutic potential of diazeniumdiolate-based aspirin prodrugs in breast cancer.The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.Design and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl.Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.Ring expansions of acyloxy nitroso compoundsBiological signaling by small inorganic moleculesThe pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NOMeningeal blood flow is controlled by H2 S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway.Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects.The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin.Modeling heme proteins using atomistic simulations.Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin.The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats.Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.Recent advances in the chemical biology of nitroxyl (HNO) detection and generation.Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method.The effects of nitroxyl (HNO) on H₂O₂ metabolism and possible mechanisms of HNO signaling.The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidationThe emergence of nitroxyl (HNO) as a pharmacological agent.
P2860
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P2860
A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A biochemical rationale for th ...... in the cardiovascular system.
@ast
A biochemical rationale for th ...... in the cardiovascular system.
@en
type
label
A biochemical rationale for th ...... in the cardiovascular system.
@ast
A biochemical rationale for th ...... in the cardiovascular system.
@en
prefLabel
A biochemical rationale for th ...... in the cardiovascular system.
@ast
A biochemical rationale for th ...... in the cardiovascular system.
@en
P2093
P2860
P356
P1476
A biochemical rationale for th ...... in the cardiovascular system.
@en
P2093
David A Kass
David A Wink
Douglas D Thomas
Eleonora Ford
Jon M Fukuto
Katrina M Miranda
Martin Feelisch
Michael D Bartberger
Michael G Espey
Nazareno Paolocci
P2860
P304
P356
10.1073/PNAS.1430507100
P407
P577
2003-07-15T00:00:00Z