Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies. - Test2 - elhamkhani - TriplyDB

Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.

Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.

http://www.wikidata.org/entity/Q35252648

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Stem Cells Applications in Regenerative Medicine and Disease Therapeutics.Understanding platelet generation from megakaryocytes: implications for in vitro-derived platelets Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics Pathophysiological Significance of Store-Operated Calcium Entry in Megakaryocyte Function: Opening New Paths for Understanding the Role of Calcium in Thrombopoiesis The European Hematology Association Roadmap for European Hematology Research: a consensus document Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients Inherited thrombocytopenias-recent advances in clinical and molecular aspects.Revealing eltrombopag's promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation Rapamycin and bafilomycin A1 alter autophagy and megakaryopoiesis.Platelet bioreactor: accelerated evolution of design and manufacture.Towards the Manufacture of Megakaryocytes and Platelets for Clinical Application.In vitro generation of platelets: Where do we stand?Presence of diabetes autoantigens in extracellular vesicles derived from human islets.Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale.Embryonic stem cells as sources of donor-independent platelets.Tissue Engineering and Regenerative Medicine 2015: A Year in Review Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage.Navigating the bone marrow niche: translational insights and cancer-driven dysfunction.Polyurethane scaffolds seeded with CD34(+) cells maintain early stem cells whilst also facilitating prolonged egress of haematopoietic progenitors.Tense your megas! Structural rigidity is key Regulation of the genetic code in megakaryocytes and platelets.The role of the extracellular matrix in primary myelofibrosis.Creating artificial lymphoid tissues to study immunity and hematological malignancies.Application of microfluidic devices in studies of thrombosis and hemostasis.Platelet production from induced pluripotent stem cells.Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis.3D models of the hematopoietic stem cell niche under steady-state and active conditions.A new path to platelet production through matrix sensing.A paradigm shift in platelet transfusion therapy.Eltrombopag, a potent stimulator of megakaryopoiesis.Innovation in the field of thrombocytopenias: achievements since the beginning of the century and promises for the future.A uniform-shear rate microfluidic bioreactor for real-time study of proplatelet formation and rapidly-released platelets.Modular flow chamber for engineering bone marrow architecture and function.Multi-layered silk film coculture system for human corneal epithelial and stromal stem cells.The role of extracellular matrix stiffness in megakaryocyte and platelet development and function.Hematopoietic Niche - Exploring Biomimetic Cues to Improve the Functionality of Hematopoietic Stem/Progenitor Cells.Multifunctional Bioreactor System for Human Intestine Tissues.Current status of blood 'pharming': megakaryoctye transfusions as a source of platelets.The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes.

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P2860

Programmable 3D silk bone marrow niche for platelet generation ex vivo and modeling of megakaryopoiesis pathologies.

http://www.wikidata.org/entity/Q35252648

description

2015 nî lūn-bûn

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2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2015 թվականի հունվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Programmable 3D silk bone marr ...... megakaryopoiesis pathologies.

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Antonella Antonelli

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Carla Sfara

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Cristian Staii

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Daniel Smoot

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Elise Spedden

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Lindsay S Wray

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Luigi De Marco

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Mauro Magnani

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Ying Chen

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P2860

Identification of a novel hierarchy of endothelial progenitor cells using human peripheral and umbilical cord blood

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.

Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes.

Megakaryocytes contribute to the bone marrow-matrix environment by expressing fibronectin, type IV collagen, and laminin

Modulation of in vitro angiogenesis in a three-dimensional spheroidal coculture model for bone tissue engineering.

Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis.

Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells.

Association of fibrin with the platelet cytoskeleton.

Adhesion and homing of blood-borne cells in bone marrow microvessels.

Dynamic niches in the origination and differentiation of haematopoietic stem cells.

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2254-2264

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10.1182/BLOOD-2014-08-595561

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14

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Alessandro Malara

Alessandra Balduini

Christian A Di Buduo

Chiara E Ghezzi

David L. Kaplan

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2015-01-09T00:00:00Z

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270706016

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25575540

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