Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein
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Is tau ready for admission to the prion club?Unfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesCellular aspects of prion replication in vitroProtein disulfide isomerase regulates endoplasmic reticulum stress and the apoptotic process during prion infection and PrP mutant-induced cytotoxicity.Ubiquitin ligase gp78 targets unglycosylated prion protein PrP for ubiquitylation and degradation.Ubiquitin-specific protease 14 modulates degradation of cellular prion proteinDysfunction of microtubule-associated proteins of MAP2/tau family in Prion disease.De novo prion aggregates trigger autophagy in skeletal muscle.Specificity and regulation of the endoplasmic reticulum-associated degradation machinery.Role of protein misfolding and proteostasis deficiency in protein misfolding diseases and aging.Prion degradation pathways: Potential for therapeutic intervention.Unfolding the promise of translational targeting in neurodegenerative disease.Multiple Mechanisms of Unfolded Protein Response-Induced Cell DeathThe Protein-disulfide Isomerase ERp57 Regulates the Steady-state Levels of the Prion Protein.FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection.Disruption of glycosylation enhances ubiquitin-mediated proteasomal degradation of Shadoo in Scrapie-infected rodents and cultured cells.Trafficking of PrPc to mitochondrial raft-like microdomains during cell apoptosis.Regulating Secretory Proteostasis through the Unfolded Protein Response: From Function to Therapy.Protein accumulation in the endoplasmic reticulum as a non-equilibrium phase transition.Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane.A role for the proteasome in the turnover of Sup35p and in [PSI(+) ] prion propagation.Iron Loading Selectively Increases Hippocampal Levels of Ubiquitinated Proteins and Impairs Hippocampus-Dependent Memory.Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.Interaction of Peptide Aptamers with Prion Protein Central Domain Promotes α-Cleavage of PrPC.Overexpression of quality control proteins reduces prion conversion in prion-infected cellsCrosstalk between Endoplasmic Reticulum Stress and Protein Misfolding in Neurodegenerative Diseases
P2860
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P2860
Proteasomal dysfunction and endoplasmic reticulum stress enhance trafficking of prion protein aggregates through the secretory pathway and increase accumulation of pathologic prion protein
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Proteasomal dysfunction and en ...... on of pathologic prion protein
@ast
Proteasomal dysfunction and en ...... on of pathologic prion protein
@en
type
label
Proteasomal dysfunction and en ...... on of pathologic prion protein
@ast
Proteasomal dysfunction and en ...... on of pathologic prion protein
@en
prefLabel
Proteasomal dysfunction and en ...... on of pathologic prion protein
@ast
Proteasomal dysfunction and en ...... on of pathologic prion protein
@en
P2093
P2860
P356
P1476
Proteasomal dysfunction and en ...... on of pathologic prion protein
@en
P2093
Hanna Wolf
Ina Vorberg
Kerstin Ackermann
Kim Dietrich
Lars Gädtke
Martin Groschup
Max Nunziante
Sabine Gilch
P2860
P304
33942-33953
P356
10.1074/JBC.M111.272617
P407
P577
2011-08-11T00:00:00Z