BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension - Test2 - elhamkhani - TriplyDB

BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension

BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension

http://www.wikidata.org/entity/Q35376926

about

BMPR2 spruces up the endothelium in pulmonary hypertension The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis DNA Damage and Pulmonary Hypertension Mitochondrial Haplogroups and Risk of Pulmonary Arterial Hypertension Emerging Metabolic Therapies in Pulmonary Arterial Hypertension.Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension The cancer theory of pulmonary arterial hypertension.Raf/ERK drives the proliferative and invasive phenotype of BMPR2-silenced pulmonary artery endothelial cells.In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension Amphetamines promote mitochondrial dysfunction and DNA damage in pulmonary hypertension Discerning functional hierarchies of microRNAs in pulmonary hypertension.Patient-Specific iPSC-Derived Endothelial Cells Uncover Pathways that Protect against Pulmonary Hypertension in BMPR2 Mutation Carriers.Restoring BMPRII functions in pulmonary arterial hypertension: opportunities, challenges and limitations.Critical effects of epigenetic regulation in pulmonary arterial hypertension.Increased Pyruvate Dehydrogenase Kinase 4 Expression in Lung Pericytes Is Associated with Reduced Endothelial-Pericyte Interactions and Small Vessel Loss in Pulmonary Arterial Hypertension.Disruption of lineage specification in adult pulmonary mesenchymal progenitor cells promotes microvascular dysfunction Update on novel targets and potential treatment avenues in pulmonary hypertension.Induced Pluripotent Stem Cell Model of Pulmonary Arterial Hypertension Reveals Novel Gene Expression and Patient Specificity.Suppression of endothelial PGC-1α is associated with hypoxia-induced endothelial dysfunction and provides a new therapeutic target in pulmonary arterial hypertension.Mitochondrial and Metabolic Drivers of Pulmonary Vascular Endothelial Dysfunction in Pulmonary Hypertension.PPARγ Regulates Mitochondrial Structure and Function and HPASMC Proliferation.Mitochondrial dysfunction and pulmonary hypertension: Cause, Effect or Both.Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA.DRUG INDUCED PULMONARY ARTERIAL HYPERTENSION: A PRIMER FOR CLINICIANS AND SCIENTISTS.Codependence of Bone Morphogenetic Protein Receptor 2 and Transforming Growth Factor-β in Elastic Fiber Assembly and Its Perturbation in Pulmonary Arterial Hypertension.Recurrent inhibition of mitochondrial complex III induces chronic pulmonary vasoconstriction and glycolytic switch in the rat lung.YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1α.Delayed Microvascular Shear Adaptation in Pulmonary Arterial Hypertension. Role of Platelet Endothelial Cell Adhesion Molecule-1 Cleavage.BMPR2 mutations and endothelial dysfunction in pulmonary arterial hypertension (2017 Grover Conference Series).Metabolic dysfunction in pulmonary hypertension: from basic science to clinical practice.Bone morphogenetic protein signaling is required for RAD51-mediated maintenance of genome integrity in vascular endothelial cells Mitochondrial metabolism in pulmonary hypertension: beyond mountains there are mountains Consequences of BMPR2 Deficiency in the Pulmonary Vasculature and Beyond: Contributions to Pulmonary Arterial Hypertension

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P2860

BMPR2 preserves mitochondrial function and DNA during reoxygenation to promote endothelial cell survival and reverse pulmonary hypertension

http://www.wikidata.org/entity/Q35376926

description

2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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type

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BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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prefLabel

BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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J.CMET.2015.03.010

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Cell Metabolism

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BMPR2 preserves mitochondrial ...... reverse pulmonary hypertension

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P2093

Aiqin Cao

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Caiyun G Li

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Isabel Diebold

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Kazuya Miyagawa

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Kiichi Nakahira

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Lijuan Ji

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Lingli Wang

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Mark Kaschwich

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Marlene Rabinovitch

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Miguel A Alejandre Alcazar

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P2860

Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis

Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis

Mitochondrial DNA mutations in human disease

An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

PGC1α-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension

Circulating mitochondrial DAMPs cause inflammatory responses to injury.

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis.

Age and sex influence on pulmonary hypertension of chronic hypoxia and on recovery.

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596-608

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10.1016/J.CMET.2015.03.010

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