Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis - Test2 - elhamkhani - TriplyDB

Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

http://www.wikidata.org/entity/Q35469063

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Biological influence of Hakai in cancer: a 10-year review The emerging role of Slit-Robo pathway in gastric and other gastro intestinal cancers Adherens junction turnover: regulating adhesion through cadherin endocytosis, degradation, and recycling Nfib Promotes Metastasis through a Widespread Increase in Chromatin Accessibility.Slit/Robo signaling modulates the proliferation of central nervous system progenitors Epithelial-mesenchymal transition associates with maintenance of stemness in spheroid-derived stem-like colon cancer cells.Slit2 overexpression results in increased microvessel density and lesion size in mice with induced endometriosis.Slit/Robo signaling regulates cell fate decisions in the intestinal stem cell lineage of Drosophila.Role of the microtubule-targeting drug vinflunine on cell-cell adhesions in bladder epithelial tumour cells.Global expression profile in low grade meningiomas and schwannomas shows upregulation of PDGFD, CDH1 and SLIT2 compared to their healthy tissue.Rpb3 promotes hepatocellular carcinoma through its N-terminus.Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation.USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration.Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway.CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment.Slit2‑Robo1 signaling promotes the adhesion, invasion and migration of tongue carcinoma cells via upregulating matrix metalloproteinases 2 and 9, and downregulating E‑cadherin.MicroRNA 203 Modulates Glioma Cell Migration via Robo1/ERK/MMP-9 Signaling.Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection.srGAP1 mediates the migration inhibition effect of Slit2-Robo1 in colorectal cancer.SOX17 is a tumor suppressor in endometrial cancer Ubiquitin links to cytoskeletal dynamics, cell adhesion and migration.A roundabout way to cancer.Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer MiR-218 inhibits the tumorgenesis and proliferation of glioma cells by targeting Robo1.SLIT2 inhibits cell migration in colorectal cancer through the AKT-GSK3β signaling pathway.N-cadherin expression level as a critical indicator of invasion in non-epithelial tumors Recombinant N-Terminal Slit2 Inhibits TGF-β-Induced Fibroblast Activation and Renal Fibrosis.HGF/R-spondin1 rescues liver dysfunction through the induction of Lgr5+ liver stem cells.SLIT3 is increased in supracervical human foetal membranes and in labouring myometrium and regulates pro-inflammatory mediators.SRGAP1, a crucial target of miR-340 and miR-124, functions as a potential oncogene in gastric tumorigenesis.Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment.Whole-Exome Sequencing-Based Mutational Profiling of Hepatitis B Virus-Related Early-Stage Hepatocellular Carcinoma.The role of Slit-Robo signaling in the regulation of tissue barriers.Candidate predisposing germline copy number variants in early onset colorectal cancer patients.Robo1 and vimentin regulate radiation-induced motility of human glioblastoma cells.Differential Integration of Transcriptome and Proteome Identifies Pan-Cancer Prognostic Biomarkers.

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Slit-Robo signaling induces malignant transformation through Hakai-mediated E-cadherin degradation during colorectal epithelial cell carcinogenesis

http://www.wikidata.org/entity/Q35469063

description

2011 nî lūn-bûn

@nan

2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2011年の論文

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2011年論文

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2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

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name

Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

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Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

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type

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Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

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Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

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prefLabel

Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

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Slit-Robo signaling induces ma ...... epithelial cell carcinogenesis

@en

P2093

Jian-Guo Geng

http://www.w3.org/2001/XMLSchema#string

Li Ma

http://www.w3.org/2001/XMLSchema#string

Li-Jing Wang

http://www.w3.org/2001/XMLSchema#string

Shan Chi

http://www.w3.org/2001/XMLSchema#string

Shu-Jue Lan

http://www.w3.org/2001/XMLSchema#string

Wei-Jie Zhou

http://www.w3.org/2001/XMLSchema#string

Wenli Zhang

http://www.w3.org/2001/XMLSchema#string

Xiao-Feng Niu

http://www.w3.org/2001/XMLSchema#string

Xuesong Yang

http://www.w3.org/2001/XMLSchema#string

Yan-Qing Ding

http://www.w3.org/2001/XMLSchema#string

P2860

Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance

The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

roundabout4 is essential for angiogenesis in vivo.

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity

Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability

HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor

The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils

P-selectin primes leukocyte integrin activation during inflammation

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609-626

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scholarly article

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10.1038/CR.2011.17

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4

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21

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2011-02-01T00:00:00Z

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49800165

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1044322902

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21283129

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3203654

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