about
Regulation of CaMKII signaling in cardiovascular diseaseSignaling effectors underlying pathologic growth and remodeling of the heartProtein kinase C mechanisms that contribute to cardiac remodellingConserved modular domains team up to latch-open active protein kinase CαAliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in miceDifferential and conditional activation of PKC-isoforms dictates cardiac adaptation during physiological to pathological hypertrophy.Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study.Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.Alteration in mitochondrial Ca(2+) uptake disrupts insulin signaling in hypertrophic cardiomyocytes.PKC activation by resveratrol derivatives with unsaturated aliphatic chainEffects of late administration of pentoxifylline and tocotrienols in an image-guided rat model of localized heart irradiationProtein phosphorylation detection using dual-mode field-effect devices and nanoplasmonic sensors.Inhibition of PKCα/β with ruboxistaurin antagonizes heart failure in pigs after myocardial infarction injury.Combined cardiomyocyte PKCδ and PKCε gene deletion uncovers their central role in restraining developmental and reactive heart growthInhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice.Agonist activated PKCβII translocation and modulation of cardiac myocyte contractile function.Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.Protein kinase C, an elusive therapeutic target?Protein phosphatase 2A is regulated by protein kinase Cα (PKCα)-dependent phosphorylation of its targeting subunit B56α at Ser41.Doxazosin Stimulates Galectin-3 Expression and Collagen Synthesis in HL-1 Cardiomyocytes Independent of Protein Kinase C PathwayProtein kinase C, focal adhesions and the regulation of cell migration.Mitochondria, myocardial remodeling, and cardiovascular disease.Molecular targets of current and prospective heart failure therapies.How cardiomyocytes sense pathophysiological stresses for cardiac remodeling.Sub-cellular localization specific SUMOylation in the heart.Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.Ginsenoside Rb1 improves cardiac function and remodeling in heart failure.Effect of PKC inhibitor on experimental autoimmune myocarditis in Lewis ratsCurcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain.Protein kinase C isozyme expression in right ventricular hypertrophy induced by pulmonary hypertension in chronically hypoxic rats.Research advances in kinase enzymes and inhibitors for cardiovascular disease treatment.Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.(-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure.Roles of PKC Isoforms in PMA-Induced Modulation of the hERG Channel (Kv11.1).In Silico Analysis of Differential Gene Expression in Three Common Rat Models of Diastolic Dysfunction.The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy.Mutant Muscle LIM Protein C58G causes cardiomyopathy through protein depletionProtein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Protein kinase Cα as a heart failure therapeutic target
@ast
Protein kinase Cα as a heart failure therapeutic target
@en
type
label
Protein kinase Cα as a heart failure therapeutic target
@ast
Protein kinase Cα as a heart failure therapeutic target
@en
prefLabel
Protein kinase Cα as a heart failure therapeutic target
@ast
Protein kinase Cα as a heart failure therapeutic target
@en
P2860
P1476
Protein kinase Cα as a heart failure therapeutic target
@en
P2093
Qinghang Liu
P2860
P304
P356
10.1016/J.YJMCC.2010.10.004
P577
2010-10-16T00:00:00Z