Biological interpretation of genome-wide association studies using predicted gene functions
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Genetic studies of body mass index yield new insights for obesity biologyProgress and promise in understanding the genetic basis of common diseasesPrediction of Causal Candidate Genes in Coronary Artery Disease LociRecent Advances and Emerging Applications in Text and Data Mining for Biomedical DiscoveryAnalysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared lociRare and low-frequency coding variants alter human adult heightLarge-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Genome-wide analysis identifies 12 loci influencing human reproductive behavior.Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraineXGR software for enhanced interpretation of genomic summary data, illustrated by application to immunological traits.Imputation of orofacial clefting data identifies novel risk loci and sheds light on the genetic background of cleft lip ± cleft palate and cleft palate only.A Novel Approach for Pathway Analysis of GWAS Data Highlights Role of BMP Signaling and Muscle Cell Differentiation in Colorectal Cancer Susceptibility.Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease.Genetic effects influencing risk for major depressive disorder in China and Europe.1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.A Proposal for a Study on Treatment Selection and Lifestyle Recommendations in Chronic Inflammatory Diseases: A Danish Multidisciplinary Collaboration on Prognostic Factors and Personalised Medicine.Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolismIdentification of 15 novel risk loci for coronary artery disease and genetic risk of recurrent events, atrial fibrillation and heart failure.52 Genetic Loci Influencing Myocardial Mass.Common shared genetic variation behind decreased risk of breast cancer in celiac disease.Genome-wide association study identifies 74 loci associated with educational attainment.Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal DevelopmentGenome-wide association studies in oesophageal adenocarcinoma and Barrett's oesophagus: a large-scale meta-analysis.Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.New genetic loci link adipose and insulin biology to body fat distribution.Fast and Rigorous Computation of Gene and Pathway Scores from SNP-Based Summary StatisticsGenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS.Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis.Meta-GWAS and Meta-Analysis of Exome Array Studies Do Not Reveal Genetic Determinants of Serum Hepcidin.A compendium of human genes regulating feeding behavior and body weight, its functional characterization and identification of GWAS genes involved in brain-specific PPI networkGenetic prediction of male pattern baldness.Genome-Wide Association Mapping for Tomato Volatiles Positively Contributing to Tomato Flavor.Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysisGenome-wide meta-analysis uncovers novel loci influencing circulating leptin levelsNew loci for body fat percentage reveal link between adiposity and cardiometabolic disease riskChronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus.Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia.Comprehensive analysis of schizophrenia-associated loci highlights ion channel pathways and biologically plausible candidate causal genes.
P2860
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P2860
Biological interpretation of genome-wide association studies using predicted gene functions
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Biological interpretation of g ...... using predicted gene functions
@ast
Biological interpretation of g ...... using predicted gene functions
@en
type
label
Biological interpretation of g ...... using predicted gene functions
@ast
Biological interpretation of g ...... using predicted gene functions
@en
prefLabel
Biological interpretation of g ...... using predicted gene functions
@ast
Biological interpretation of g ...... using predicted gene functions
@en
P2093
P2860
P50
P356
P1476
Biological interpretation of g ...... using predicted gene functions
@en
P2093
Andrew R Wood
Elizabeth K Speliotes
Genetic Investigation of ANthropometric Traits (GIANT) Consortium
Joel N Hirschhorn
Juha M Karjalainen
Julian C Lui
Rudolf S N Fehrmann
Sailaja Vedantam
Soumya Raychaudhuri
Tim Frayling
P2860
P2888
P356
10.1038/NCOMMS6890
P407
P50
P577
2015-01-19T00:00:00Z