Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism.
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Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cellsMaternal hypoxia decreases capillary supply and increases metabolic inefficiency leading to divergence in myocardial oxygen supply and demandComputational model of cellular metabolic dynamics: effect of insulin on glucose disposal in human skeletal muscle.Effects of meal frequency on metabolic profiles and substrate partitioning in lean healthy males.Mechanisms of insulin resistance in non-oxidative glucose metabolism: the role of glycogen synthase.Insulin resistance is not conserved in myotubes established from women with PCOS.Pathogenesis of insulin resistance in skeletal muscle.Characterization of cellular defects of insulin action in type 2 (non-insulin-dependent) diabetes mellitusSkeletal muscle glycogenolysis is more sensitive to insulin than is glucose transport/phosphorylation. Relation to the insulin-mediated inhibition of hepatic glucose productionCardiac energy metabolism and oxidative stress biomarkers in diabetic rat treated with resveratrol.Molecular basis of canine muscle type phosphofructokinase deficiency.Interaction between glucose and free fatty acid metabolism in human skeletal muscleMultiple defects in muscle glycogen synthase activity contribute to reduced glycogen synthesis in non-insulin dependent diabetes mellitusDefective insulin response of cyclic adenosine monophosphate-dependent protein kinase in insulin-resistant humans.Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle.Regulation of PDH in human arm and leg muscles at rest and during intense exercise.Effects of insulin and oral anti-diabetic agents on glucose metabolism, vascular dysfunction and skeletal muscle inflammation in type 2 diabetic subjects.Impaired insulin-stimulated muscle glycogen synthase activation in vivo in man is related to low fasting glycogen synthase phosphatase activity31P nuclear magnetic resonance measurements of muscle glucose-6-phosphate. Evidence for reduced insulin-dependent muscle glucose transport or phosphorylation activity in non-insulin-dependent diabetes mellitus.Glycogen synthase and phosphofructokinase protein and mRNA levels in skeletal muscle from insulin-resistant patients with non-insulin-dependent diabetes mellitus.Hyperglycemia normalizes insulin-stimulated skeletal muscle glucose oxidation and storage in noninsulin-dependent diabetes mellitus.Exercise with calorie restriction improves insulin sensitivity and glycogen synthase activity in obese postmenopausal women with impaired glucose toleranceAge-related impairments in skeletal muscle PDH phosphorylation and plasma lactate are indicative of metabolic inflexibility and the effects of exercise training.Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitusInsulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscleGlycogen synthase activity is reduced in cultured skeletal muscle cells of non-insulin-dependent diabetes mellitus subjects. Biochemical and molecular mechanisms.The role of glycogen synthase in the development of hyperglycemia in type 2 diabetes: 'To store or not to store glucose, that's the question'.Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challengePyruvate Dehydrogenase Activity Is Decreased in Emergency Department Patients With Diabetic Ketoacidosis.Effects of physiological hyperinsulinemia on the intracellular metabolic partition of plasma glucose.Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus.Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats.Decreased insulin activation of glycogen synthase in skeletal muscles in young nonobese Caucasian first-degree relatives of patients with non-insulin-dependent diabetes mellitus.Glucose transport in human skeletal muscle cells in culture. Stimulation by insulin and metformin.In skeletal muscle, glucose storage and oxidation are differentially impaired by the IR1152 mutant receptor.Skeletal muscle glycogen synthase subcellular localization: effects of insulin and PPAR-alpha agonist (K-111) administration in rhesus monkeys.Effects of hyperthyroidism on the sensitivity of glycolysis and glycogen synthesis to insulin in the soleus muscle of the rat.Physiological hyperinsulinemia impairs insulin-stimulated glycogen synthase activity and glycogen synthesis.Carbohydrate ingestion reduces skeletal muscle acetylcarnitine availability but has no effect on substrate phosphorylation at the onset of exercise in man.Unlike insulin, amino acids stimulate p70S6K but not GSK-3 or glycogen synthase in human skeletal muscle.
P2860
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P2860
Effects of insulin infusion on human skeletal muscle pyruvate dehydrogenase, phosphofructokinase, and glycogen synthase. Evidence for their role in oxidative and nonoxidative glucose metabolism.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
Effects of insulin infusion on ...... noxidative glucose metabolism.
@ast
Effects of insulin infusion on ...... noxidative glucose metabolism.
@en
type
label
Effects of insulin infusion on ...... noxidative glucose metabolism.
@ast
Effects of insulin infusion on ...... noxidative glucose metabolism.
@en
prefLabel
Effects of insulin infusion on ...... noxidative glucose metabolism.
@ast
Effects of insulin infusion on ...... noxidative glucose metabolism.
@en
P2093
P2860
P356
P1476
Effects of insulin infusion on ...... noxidative glucose metabolism.
@en
P2093
H Beck-Nielsen
K S Wright
L J Mandarino
L S Verity
O G Kolterman
P2860
P304
P356
10.1172/JCI113118
P407
P577
1987-09-01T00:00:00Z