Proteasome-mediated degradation of integral inner nuclear membrane protein emerin in fibroblasts lacking A-type lamins

Proteasome-mediated degradation of integral inner nuclear membrane protein emerin in fibroblasts lacking A-type lamins

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http://www.wikidata.org/entity/Q35589666
LULL1 retargets TorsinA to the nuclear envelope revealing an activity that is impaired by the DYT1 dystonia mutationThe ubiquitin-proteasome system and nonsense-mediated mRNA decay in hypertrophic cardiomyopathyLamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10"Laminopathies": a wide spectrum of human diseases.Ubiquitin ligase RNF123 mediates degradation of heterochromatin protein 1α and β in lamin A/C knock-down cells.Sustained accumulation of prelamin A and depletion of lamin A/C both cause oxidative stress and mitochondrial dysfunction but induce different cell fatesQuantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide.Reduced expression of A-type lamins and emerin activates extracellular signal-regulated kinase in cultured cells.The expression of Lamin A mutant R321X leads to endoplasmic reticulum stress with aberrant Ca2+ handling.Lamins, laminopathies and disease mechanisms: possible role for proteasomal degradation of key regulatory proteins.A nuclear ubiquitin-proteasome pathway targets the inner nuclear membrane protein Asi2 for degradation.Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells.
P2860

Proteasome-mediated degradation of integral inner nuclear membrane protein emerin in fibroblasts lacking A-type lamins

Item
http://www.wikidata.org/entity/Q35589666
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@ast
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@en
type
label
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@ast
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@en
prefLabel
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@ast
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P356
P1433
P1476
Proteasome-mediated degradatio ...... roblasts lacking A-type lamins
@en
P2093
P2860
P304
P31
P356
10.1016/J.BBRC.2006.10.147
P407
P433
P478
P50
P577
P5875
P698
P932