Discovering new medicines targeting helicases: challenges and recent progress. - Test2 - elhamkhani - TriplyDB

Discovering new medicines targeting helicases: challenges and recent progress.

Discovering new medicines targeting helicases: challenges and recent progress.

http://www.wikidata.org/entity/Q35592783

about

New strategies against drug resistance to herpes simplex virus DDX3, a potential target for cancer treatment The Mcm2-7 replicative helicase: a promising chemotherapeutic target Targeting the ATP-dependent formation of herpesvirus ribonucleoprotein particle assembly as an antiviral approach Inhibition of a Putative Dihydropyrimidinase from Pseudomonas aeruginosa PAO1 by Flavonoids and Substrates of Cyclic Amidohydrolases Interactive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.RECQL1 and WRN DNA repair helicases: potential therapeutic targets and proliferative markers against cancers.Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase.DNA-conjugated gold nanoparticles based colorimetric assay to assess helicase activity: a novel route to screen potential helicase inhibitors Functional interplay among the flavivirus NS3 protease, helicase, and cofactors.Helicases, G4-DNAs, and drug design.Design and development of antivirals and intervention strategies against human herpesviruses using high-throughput approach.New developments in flavivirus drug discovery.Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.Versatility of 7-Substituted Coumarin Molecules as Antimycobacterial Agents, Neuronal Enzyme Inhibitors and Neuroprotective Agents.Identification of inhibitors of Plasmodium falciparum RuvB1 helicase using biochemical assays.ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A.DNA Replication Fidelity in the Mycobacterium tuberculosis Complex.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy Chemical genetic inhibition of DEAD-box proteins using covalent complementarity

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P2860

Discovering new medicines targeting helicases: challenges and recent progress.

http://www.wikidata.org/entity/Q35592783

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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Discovering new medicines targeting helicases: challenges and recent progress.

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Discovering new medicines targeting helicases: challenges and recent progress.

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Discovering new medicines targeting helicases: challenges and recent progress.

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Discovering new medicines targeting helicases: challenges and recent progress.

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Discovering new medicines targeting helicases: challenges and recent progress.

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Journal of Biomolecular Screening

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Discovering new medicines targeting helicases: challenges and recent progress.

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Alicia M Hanson

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Jean Ndjomou

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Rajesh Kolli

http://www.w3.org/2001/XMLSchema#string

Sourav Mukherjee

http://www.w3.org/2001/XMLSchema#string

William R Shadrick

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs

The Werner syndrome protein is a DNA helicase

Cellular RNA helicase p68 relocalization and interaction with the hepatitis C virus (HCV) NS5B protein and the potential role of p68 in HCV RNA replication

The evolutionary history of methicillin-resistant Staphylococcus aureus (MRSA)

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation.

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold

Disease-causing missense mutations in human DNA helicase disorders

Perspective: test and treat this silent killer.

Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.

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7

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23536547

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4427233

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