Phospholipase D: enzymology, functionality, and chemical modulation
about
Hyperactivation of EGFR and downstream effector phospholipase D1 by oncogenic FAM83BThe role of amino acid-induced mammalian target of rapamycin complex 1(mTORC1) signaling in insulin resistanceBacterial Sphingomyelinases and Phospholipases as Virulence FactorsRegulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane TargetingRecombinant Lipases and Phospholipases and Their Use as Biocatalysts for Industrial ApplicationsFunctional regulation of phospholipase D expression in cancer and inflammationDrugs for allosteric sites on receptorsMechanism of enzymatic reaction and protein-protein interactions of PLD from a 3D structural model.The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesisThe phospholipase D superfamily as therapeutic targetsHow independent pharmacological screenings in plants and humans led to the discovery of a new family of lipid metabolism inhibitorsPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsPhospholipase D2 mediates signaling by ATPase class I type 8B membrane 1Progress of small molecular inhibitors in the development of anti-influenza virus agents.The Concise Guide to PHARMACOLOGY 2013/14: enzymes.Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolone analogs.Choline's role in maintaining liver function: new evidence for epigenetic mechanisms.Phospholipase D in cell signaling: from a myriad of cell functions to cancer growth and metastasis.Phospholipase D facilitates efficient entry of influenza virus, allowing escape from innate immune inhibitionDiscovery of a new ATP-binding motif involved in peptidic azoline biosynthesis.Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid.2013 Philip S. Portoghese Medicinal Chemistry Lectureship: drug discovery targeting allosteric sites.Phospholipase D signaling pathways and phosphatidic acid as therapeutic targets in cancerPhospholipase D toxins of brown spider venom convert lysophosphatidylcholine and sphingomyelin to cyclic phosphatesIdentification of two Legionella pneumophila effectors that manipulate host phospholipids biosynthesisPotential Implications for Designing Drugs Against the Brown Spider Venom Phospholipase-D.Identification of new sphingomyelinases D in pathogenic fungi and other pathogenic organisms.Phospholipase D1 protein coordinates dynamic assembly of HIF-1α-PHD-VHL to regulate HIF-1α stabilityDiscovery of desketoraloxifene analogues as inhibitors of mammalian, Pseudomonas aeruginosa, and NAPE phospholipase D enzymes.Detection of choline and phosphatidic acid (PA) catalyzed by phospholipase D (PLD) using MALDI-QIT-TOF/MS with 9-aminoacridine matrix.Butanol isomers exert distinct effects on voltage-gated calcium channel currents and thus catecholamine secretion in adrenal chromaffin cells.Phospholipase D2 is involved in the formation of Golgi tubules and ArfGAP1 recruitmentVariable Substrate Preference among Phospholipase D Toxins from Sicariid Spiders.Human phospholipase D activity transiently regulates pyrimidine biosynthesis in malignant gliomasFrom guide to target: molecular insights into eukaryotic RNA-interference machinery.Modulation of Insulin Sensitivity of Hepatocytes by the Pharmacological Downregulation of Phospholipase D.Acinetobacter baumannii Virulence Is Mediated by the Concerted Action of Three Phospholipases D.Targeting phospholipase D1 attenuates intestinal tumorigenesis by controlling β-catenin signaling in cancer-initiating cells.Discovery of a highly selective PLD2 inhibitor (ML395): a new probe with improved physiochemical properties and broad-spectrum antiviral activity against influenza strainsThe Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia.
P2860
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P2860
Phospholipase D: enzymology, functionality, and chemical modulation
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Phospholipase D: enzymology, functionality, and chemical modulation
@ast
Phospholipase D: enzymology, functionality, and chemical modulation
@en
type
label
Phospholipase D: enzymology, functionality, and chemical modulation
@ast
Phospholipase D: enzymology, functionality, and chemical modulation
@en
prefLabel
Phospholipase D: enzymology, functionality, and chemical modulation
@ast
Phospholipase D: enzymology, functionality, and chemical modulation
@en
P2093
P2860
P356
P1433
P1476
Phospholipase D: enzymology, functionality, and chemical modulation
@en
P2093
H Alex Brown
Paige E Selvy
Robert R Lavieri
P2860
P304
P356
10.1021/CR200296T
P577
2011-09-22T00:00:00Z