Protein kinase-inhibitor database: structural variability of and inhibitor interactions with the protein kinase P-loop.
about
Electrophilic Fragment-Based Design of Reversible Covalent Kinase InhibitorsMechanisms of drug resistance in kinases.Docking challenge: protein sampling and molecular docking performance.Determining Cysteines Available for Covalent Inhibition Across the Human Kinome.Computational study of Gleevec and G6G reveals molecular determinants of kinase inhibitor selectivity.Structure-based lead discovery for protein kinase C zeta inhibitor design by exploiting kinase-inhibitor complex crystal structure data and potential therapeutics for preterm labour.Identification of Highly Potent Protein Kinase C-Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing.Optimal strategies for virtual screening of induced-fit and flexible target in the 2015 D3R Grand ChallengeDevelopment of a highly selective c-Src kinase inhibitor.Irreversible inhibitors of c-Src kinase that target a nonconserved cysteine.Insights from Pim1 structure for anti-cancer drug design.Conformational flexibility of human casein kinase catalytic subunit explored by metadynamics.Specificity rendering 'hot-spots' for aurora kinase inhibitor design: the role of non-covalent interactions and conformational transitions.Kinase-targeted cancer therapies: progress, challenges and future directions.Molecular dynamics simulation reveals structural and thermodynamic features of kinase activation by cancer mutations within the epidermal growth factor receptor.
P2860
Q27677115-5A1EE09D-2CB2-4846-BBAA-818A72D1A317Q27692567-3826D4C1-817B-42A3-8977-BF1E381C95BBQ30607323-DE479185-46C5-4278-9B57-7ECCAE07E1E5Q33859476-F4D5613A-DC2C-4D4F-BDF8-EBF42FE53458Q34408156-CD39F37F-8941-4C8D-BEDF-8A2FDCD9DCAEQ35328393-48056BBA-AA4C-4E9B-8145-B95FD2E3E8DCQ36089876-B4113026-AFE2-4E86-8BA6-9DBDED8EBC69Q36116506-792C2937-4AEF-4F17-90AB-5CC954B111B2Q36177311-A8EF993E-185A-4566-ABC7-4A2B9588001FQ36405755-9A23921E-E279-4B18-90F8-19C8FD582824Q38045948-1D65827B-2579-4047-9B04-F8548DF58110Q39759976-1981EF81-4C9B-4F8C-85EE-F1F133ED3A96Q41717003-D05EF435-E843-4192-B4DB-9389388F693BQ49887882-D0F97F6C-F348-494D-85D3-3CCF65E26E06Q54577949-C890850F-1EA5-437B-9539-4B0B88870FDC
P2860
Protein kinase-inhibitor database: structural variability of and inhibitor interactions with the protein kinase P-loop.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@ast
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@en
type
label
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@ast
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@en
prefLabel
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@ast
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@en
P2860
P356
P1476
Protein kinase-inhibitor datab ...... ith the protein kinase P-loop.
@en
P2093
Robert J Doerksen
Ronak Y Patel
P2860
P304
P356
10.1021/PR100662S
P577
2010-09-01T00:00:00Z