mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine - Test2 - elhamkhani - TriplyDB

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

http://www.wikidata.org/entity/Q35609031

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Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration Stem cells as cellular vehicles for gene therapy against glioblastoma Developing an effective gene therapy for prostate cancer: New technologies with potential to translate from the laboratory into the clinic Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes MDA-7/IL-24 induces Bcl-2 denitrosylation and ubiquitin-degradation involved in cancer cell apoptosis A novel splicing variant of mouse interleukin (IL)-24 antagonizes IL-24-induced apoptosis Recombinant interleukin-24 lacks apoptosis-inducing properties in melanoma cells.Cisplatin enhances protein kinase R-like endoplasmic reticulum kinase- and CD95-dependent melanoma differentiation-associated gene-7/interleukin-24-induced killing in ovarian carcinoma cells Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.Mechanism of autophagy to apoptosis switch triggered in prostate cancer cells by antitumor cytokine melanoma differentiation-associated gene 7/interleukin-24 BI-69A11 enhances susceptibility of colon cancer cells to mda-7/IL-24-induced growth inhibition by targeting Akt MDA-7/IL-24-induced cell killing in malignant renal carcinoma cells occurs by a ceramide/CD95/PERK-dependent mechanism.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant glioma PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells.Splicing and splice factor SRp55 participate in the response to DNA damage by changing isoform ratios of target genes.MDA-7/IL-24 as a cancer therapeutic: from bench to bedside.Tumour suppressor function of MDA-7/IL-24 in human breast cancer The development of MDA-7/IL-24 as a cancer therapeutic A first-generation multi-functional cytokine for simultaneous optical tracking and tumor therapy Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.Enhancing mda-7/IL-24 therapy in renal carcinoma cells by inhibiting multiple protective signaling pathways using sorafenib and by Ad.5/3 gene delivery A serotype 5/3 adenovirus expressing MDA-7/IL-24 infects renal carcinoma cells and promotes toxicity of agents that increase ROS and ceramide levels.Myeloid cells migrate in response to IL-24.Chapter One---Cancer terminator viruses and approaches for enhancing therapeutic outcomes.Mechanism by which Mcl-1 regulates cancer-specific apoptosis triggered by mda-7/IL-24, an IL-10-related cytokine Enhanced delivery of mda-7/IL-24 using a serotype chimeric adenovirus (Ad.5/3) in combination with the Apogossypol derivative BI-97C1 (Sabutoclax) improves therapeutic efficacy in low CAR colorectal cancer cells Strategy for reversing resistance to a single anticancer agent in human prostate and pancreatic carcinomas MDA-7/IL-24: multifunctional cancer killing cytokine Dynamic changes in host gene expression associated with H5N8 avian influenza virus infection in mice.Ionizing radiation enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human ovarian cancer.Oncolytic adenovirus armed with IL-24 inhibits the growth of breast cancer in vitro and in vivo.Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis.Melanoma differentiation associated gene-7 (mda-7)/IL-24: a 'magic bullet' for cancer therapy?Histone deacetylase inhibitors interact with melanoma differentiation associated-7/interleukin-24 to kill primary human glioblastoma cells.Selected approaches for rational drug design and high throughput screening to identify anti-cancer molecules IL-24: a classic cytokine and/or a potential cure for cancer?TAT-IL-24-KDEL-induced apoptosis is inhibited by survivin but restored by the small molecular survivin inhibitor, YM155, in cancer cells.Suppression effect of recombinant adenovirus vector containing hIL-24 on Hep-2 laryngeal carcinoma cells.Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

http://www.wikidata.org/entity/Q35609031

description

2006 nî lūn-bûn

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2006年论文

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2006年论文

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name

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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type

label

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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prefLabel

mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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J.PHARMTHERA.2005.11.005

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Pharmacology & Therapeutics

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mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine

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Devanand Sarkar

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Irina V Lebedeva

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Luni Emdad

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Michael A Bachelor

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Moira Sauane

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Pankaj Gupta

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Paul B Fisher

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Steven Grant

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Zao-zhong Su

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A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface

CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity

Cloning, expression and initial characterization of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)

Interleukin-10 and the interleukin-10 receptor

Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines

Identification and functional characterization of a second chain of the interleukin-10 receptor complex.

Mammalian GADD34, an apoptosis- and DNA damage-inducible gene

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596-628

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10.1016/J.PHARMTHERA.2005.11.005

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3

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111

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David T. Curiel

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7308917

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1781515

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