Ultrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback.
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Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell ResponsesUltrasensitivity part III: cascades, bistable switches, and oscillatorsDual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1Enzyme Sequestration as a Tuning Point in Controlling Response Dynamics of Signalling NetworksIntrinsically disordered proteins in cellular signalling and regulation.Cdk1 plays matchmaker for the Polo-like kinase and its activator SPAT-1/Bora.Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching.Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR.Multisite Phosphorylation Modulates the T Cell Receptor ζ-Chain Potency but not the Switchlike Response.Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies.Robustness of MEK-ERK Dynamics and Origins of Cell-to-Cell Variability in MAPK Signaling.The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/CksLong-term dynamics of multisite phosphorylationThresholds and ultrasensitivity from negative cooperativity.Posttranscriptional regulation of uridine diphosphate glucuronosyltransferases.Emerging mechanisms regulating mitotic synchrony during animal embryogenesis.Identifying ultrasensitive HGF dose-response functions in a 3D mammalian system for synthetic morphogenesis.Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations.CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets.Micromanaging checkpoint proteinsNonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean.Reciprocal regulation between mRNA and microRNA enables a bistable switch that directs cell fate decisions.Cell-cycle transitions: a common role for stoichiometric inhibitors.Competing memories of mitogen and p53 signalling control cell-cycle entry.Illuminating the Cell's Biochemical Activity Architecture.The PAR proteins: from molecular circuits to dynamic self-stabilizing cell polarity.Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G2/M-phase transition.Enzyme sequestration by the substrate: An analysis in the deterministic and stochastic domains.Systems modelling of the EGFR-PYK2-c-Met interaction network predicts and prioritizes synergistic drug combinations for triple-negative breast cancer.A thermodynamic model for multivalency in 14-3-3 protein-protein interactionsProtein–protein interactions generate hidden feedback and feed-forward loops to trigger bistable switches, oscillations and biphasic dose–responses
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Ultrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@ast
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@en
type
label
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@ast
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@en
prefLabel
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@ast
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@en
P2860
P1476
Ultrasensitivity part II: mult ...... bitors, and positive feedback.
@en
P2093
James E Ferrell
Sang Hoon Ha
P2860
P304
P356
10.1016/J.TIBS.2014.09.003
P577
2014-10-23T00:00:00Z