Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.
about
Genetic and epigenetic changes in sporadic endocrine tumors: parathyroid tumorsA mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutationGata3-deficient mice develop parathyroid abnormalities due to dysregulation of the parathyroid-specific transcription factor Gcm2MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.Identification of somatic mutations in parathyroid tumors using whole-exome sequencingFamilial isolated pituitary adenomas: from genetics to therapy.Mice deleted for cell division cycle 73 gene develop parathyroid and uterine tumours: model for the hyperparathyroidism-jaw tumour syndromeA mouse model for inherited renal fibrosis associated with endoplasmic reticulum stress.Genetically engineered mouse models of pituitary tumorsMEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.Clinical and molecular genetics of parathyroid neoplasmsA Histopathological Study of Multi-hormone Producing Proliferative Lesions in Estrogen-induced Rat Pituitary Prolactinoma.Menin and p53 have non-synergistic effects on tumorigenesis in miceReversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene.Mouse models of inherited cancer syndromesAutosomal dominant hypercalciuria in a mouse model due to a mutation of the epithelial calcium channel, TRPV5Osteoblast menin regulates bone mass in vivo.Exploring the tumors of multiple endocrine neoplasia type 1 in mouse models for basic and preclinical studiesHeterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort.Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors.Consequence of Menin Deficiency in Mouse Adipocytes Derived by In Vitro DifferentiationThe Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).Pro-oncogenic Roles of HLXB9 Protein in Insulinoma Cells through Interaction with Nono Protein and Down-regulation of the c-Met Inhibitor Cblb (Casitas B-lineage Lymphoma b).Mouse models of adrenocortical tumors.Animal models of pituitary neoplasiaPasireotide Therapy of Multiple Endocrine Neoplasia Type 1-Associated Neuroendocrine Tumors in Female Mice Deleted for an Men1 Allele Improves Survival and Reduces Tumor Progression.Genetic and epigenetic mutations of tumor suppressive genes in sporadic pituitary adenomaGenetic aspects of adrenocortical tumours and hyperplasias.Menin: a scaffold protein that controls gene expression and cell signaling.Genetic mutations in sporadic pituitary adenomas--what to screen for?Adrenocortical growth and cancer.New potential targets for treatment of Cushing's disease: epithelial growth factor receptor and cyclin-dependent kinases.Colocalization methods in pituitary tumorigenesis aged-related in MEN1 KO and wild type mice.MAJOR MOLECULAR GENETIC DRIVERS IN SPORADIC PRIMARY HYPERPARATHYROIDISM.A MEN1 pancreatic neuroendocrine tumour mouse model under temporal control.The future: genetics advances in MEN1 therapeutic approaches and management strategies.Functional Defects From Endocrine Disease-Associated Mutations in HLXB9 and Its Interacting Partner, NONO.Endocrine Disorders
P2860
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P2860
Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@ast
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@en
type
label
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@ast
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@en
prefLabel
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@ast
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@en
P2093
P2860
P356
P1476
Multiple endocrine neoplasia t ...... a and hypercorticosteronaemia.
@en
P2093
Anita A C Reed
Brian Harding
Gerard V Walls
Hilda Tateossian
Jeshmi Jeyabalan
Michael R Bowl
Michael T Cheeseman
Nicky Sullivan
Olaf Ansorge
Tertius Hough
P2860
P304
P356
10.1677/ERC-09-0082
P577
2009-07-20T00:00:00Z