Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. - Test2 - elhamkhani - TriplyDB

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

http://www.wikidata.org/entity/Q35645641

about

Efficient immunoglobulin gene disruption and targeted replacement in rabbit using zinc finger nucleases The DNA-damage response in human biology and disease Navigational mechanisms of migrating monarch butterflies Gene targeting in the rat: advances and opportunities Expression and purification of BmrI restriction endonuclease and its N-terminal cleavage domain variants Progress and prospects: zinc-finger nucleases as gene therapy agents Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification Customizing the genome as therapy for the β-hemoglobinopathies Genome-editing Technologies for Gene and Cell Therapy Towards a new era in medicine: therapeutic genome editing Origins of Programmable Nucleases for Genome Engineering From Gene Targeting to Genome Editing: Transgenic animals applications and beyond Transgenic trait deployment using designed nucleases Pluripotent stem cells and gene therapy Quantifying on- and off-target genome editing Current and Emerging Therapies for the Treatment of Cystic Fibrosis or Mitigation of Its Symptoms Liver-targeted gene therapy: Approaches and challenges Therapeutic genome editing: prospects and challenges In vivo genome editing restores haemostasis in a mouse model of haemophilia Distinct factors control histone variant H3.3 localization at specific genomic regions Enhancing Targeted Genomic DNA Editing in Chicken Cells Using the CRISPR/Cas9 System Repair at single targeted DNA double-strand breaks in pluripotent and differentiated human cells Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.Integration site selection by retroviral vectors: molecular mechanism and clinical consequences.Group II intron-based gene targeting reactions in eukaryotes.Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).Attenuation of zinc finger nuclease toxicity by small-molecule regulation of protein levels.An engineered zinc finger protein reveals a role for the insulin VNTR in the regulation of the insulin and adjacent IGF2 genes.Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays Modular system for the construction of zinc-finger libraries and proteins.Progress and prospects: techniques for site-directed mutagenesis in animal models.Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery.Design of a colicin E7 based chimeric zinc-finger nuclease Gene correction by homologous recombination with zinc finger nucleases in primary cells from a mouse model of a generic recessive genetic disease.p53 Gene repair with zinc finger nucleases optimised by yeast 1-hybrid and validated by Solexa sequencing.Sequence conversion by single strand oligonucleotide donors via non-homologous end joining in mammalian cells

P2860

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P2860

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases.

http://www.wikidata.org/entity/Q35645641

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Erica A Moehle

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Fyodor D Urnov

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Jeremy M Rock

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Michael C Holmes

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Philip D Gregory

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Russell C DeKelver

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Ya-Li Lee

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Yann Jouvenot

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P2860

The replication of DNA in Escherichia coli

Regulation and mechanisms of mammalian double-strand break repair

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses

Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A

Genome maintenance mechanisms for preventing cancer

Design and selection of novel Cys2His2 zinc finger proteins

Enhancing gene targeting with designed zinc finger nucleases

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1802009

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