An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening. - Test2 - elhamkhani - TriplyDB

An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.

An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.

http://www.wikidata.org/entity/Q35665032

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Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones Preclinical Models for Investigation of Herbal Medicines in Liver Diseases: Update and Perspective Zebrafish: an important tool for liver disease research A fresh look at zebrafish from the perspective of cancer research Emergence of zebrafish models in oncology for validating novel anticancer drug targets and nanomaterials Zebrafish and Medaka: new model organisms for modern biomedical research Zebrafish as a disease model for studying human hepatocellular carcinoma Liver-specific expressions of HBx and src in the p53 mutant trigger hepatocarcinogenesis in zebrafish Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma Quantitative in vivo optical tomography of cancer progression & vasculature development in adult zebrafish Advancements in zebrafish applications for 21st century toxicology.Serotonin Activated Hepatic Stellate Cells Contribute to Sex Disparity in Hepatocellular Carcinoma.Zebrafish models in translational research: tipping the scales toward advancements in human health.Cdc6 cooperates with c-Myc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish.Zebrafish cancer: the state of the art and the path forward.Transgenic fish systems and their application in ecotoxicology.Establishment of HRAS(G12V) transgenic medaka as a stable tumor model for in vivo screening of anticancer drugs Myc-induced liver tumors in transgenic zebrafish can regress in tp53 null mutation.Oncogenic KRAS promotes malignant brain tumors in zebrafish.Synergistic Induction of Potential Warburg Effect in Zebrafish Hepatocellular Carcinoma by Co-Transgenic Expression of Myc and xmrk Oncogenes Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration.Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish.Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio.ZEBRAFISH AS AN IN VIVO MODEL FOR SUSTAINABLE CHEMICAL DESIGN.Development of a conditional liver tumor model by mifepristone-inducible Cre recombination to control oncogenic kras V12 expression in transgenic zebrafish.The Zebrafish as a Tool to Cancer Drug Discovery.Zebrafish models of human liver development and disease A transgenic zebrafish liver tumor model with inducible Myc expression reveals conserved Myc signatures with mammalian liver tumors.The expanding role of fish models in understanding non-alcoholic fatty liver disease.Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway.Males develop faster and more severe hepatocellular carcinoma than females in krasV12 transgenic zebrafish.Chemical inhibition reveals differential requirements of signaling pathways in krasV12- and Myc-induced liver tumors in transgenic zebrafish.Zebrafish models of cancer: progress and future challenges The promise of zebrafish as a chemical screening tool in cancer therapy.The renewed battle against RAS-mutant cancers.Activation of MEK2 is sufficient to induce skin papilloma formation in transgenic zebrafish.Optical Control of Tumor Induction in the Zebrafish Resveratrol inhibits age-dependent spontaneous tumorigenesis by SIRT1-mediated post-translational modulations in the annual fish Nothobranchius guentheri.Transcriptomic analysis of a transgenic zebrafish hepatocellular carcinoma model reveals a prominent role of immune responses in tumour progression and regression.Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish.

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P2860

An inducible kras(V12) transgenic zebrafish model for liver tumorigenesis and chemical drug screening.

http://www.wikidata.org/entity/Q35665032

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

An inducible kras(V12) transge ...... s and chemical drug screening.

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An inducible kras(V12) transge ...... s and chemical drug screening.

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type

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An inducible kras(V12) transge ...... s and chemical drug screening.

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An inducible kras(V12) transge ...... s and chemical drug screening.

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An inducible kras(V12) transge ...... s and chemical drug screening.

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An inducible kras(V12) transge ...... s and chemical drug screening.

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An inducible kras(V12) transge ...... is and chemical drug screening

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Anh Tuan Nguyen

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Chor Hui Vivien Koh

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Jan M Spitsbergen

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Serguei Parinov

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Zhiyuan Gong

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P2860

Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers.

Targeting RAS signalling pathways in cancer therapy

A high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafish

Cancer. Addiction to oncogenes--the Achilles heal of cancer

Hepatocellular carcinoma pathogenesis: from genes to environment

Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer

Requirement of vasculogenesis and blood circulation in late stages of liver growth in zebrafish.

Zebrafish models for cancer.

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63-72

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1

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5

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Alexander Emelyanov

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21903676

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3255544

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