Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex
about
Signal recognition initiates reorganization of the presequence translocase during protein import.The INA complex facilitates assembly of the peripheral stalk of the mitochondrial F1Fo-ATP synthaseThe channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent mannerNMR analyses on the interactions of the yeast Tim50 C-terminal region with the presequence and Tim50 core domain.Presequence recognition by the tom40 channel contributes to precursor translocation into the mitochondrial matrixThe presequence pathway is involved in protein sorting to the mitochondrial outer membrane.Reliable identification of cross-linked products in protein interaction studies by 13C-labeled p-benzoylphenylalanine.Mitochondrial protein synthesis, import, and assembly.Molecular insights revealing interaction of Tim23 and channel subunits of presequence translocaseRole of Tim17 in coupling the import motor to the translocation channel of the mitochondrial presequence translocase.Tim50 in Trypanosoma brucei possesses a dual specificity phosphatase activity and is critical for mitochondrial protein import.Two distinct membrane potential-dependent steps drive mitochondrial matrix protein translocation.Mechanisms of protein sorting in mitochondriaMitochondrial protein homeostasis.Import of ribosomal proteins into yeast mitochondria.Role of membrane contact sites in protein import into mitochondria.How lipids modulate mitochondrial protein import.CAMK1 phosphoinositide signal-mediated protein sorting and transport network in human hepatocellular carcinoma (HCC) by biocomputation.Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids.Targeting mitochondria: how intravacuolar bacterial pathogens manipulate mitochondria.The TIM23 mitochondrial protein import complex: function and dysfunction.Cation selectivity of the presequence translocase channel Tim23 is crucial for efficient protein import.Cardiolipin mediates membrane and channel interactions of the mitochondrial TIM23 protein import complex receptor Tim50.Role of Tim17 Transmembrane Regions in Regulating the Architecture of Presequence Translocase and Mitochondrial DNA Stability.The structure of Tim50(164-361) suggests the mechanism by which Tim50 receives mitochondrial presequences.Structural changes in the mitochondrial Tim23 channel are coupled to the proton-motive force.Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces.Voltage-coupled conformational dynamics of mitochondrial protein-import channel.Mitochondrial epileptic encephalopathy, 3-methylglutaconic aciduria and variable complex V deficiency associated with TIMM50 mutations.Motor recruitment to the TIM23 channel's lateral gate restricts polypeptide release into the inner membraneMutations in compromise cell survival in OxPhos-dependent metabolic conditions
P2860
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P2860
Tim50's presequence receptor domain is essential for signal driven transport across the TIM23 complex
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Tim50's presequence receptor d ...... sport across the TIM23 complex
@ast
Tim50's presequence receptor d ...... sport across the TIM23 complex
@en
type
label
Tim50's presequence receptor d ...... sport across the TIM23 complex
@ast
Tim50's presequence receptor d ...... sport across the TIM23 complex
@en
prefLabel
Tim50's presequence receptor d ...... sport across the TIM23 complex
@ast
Tim50's presequence receptor d ...... sport across the TIM23 complex
@en
P2093
P2860
P50
P356
P1476
Tim50's presequence receptor d ...... sport across the TIM23 complex
@en
P2093
Bernard Guiard
Bernhard Schmidt
Christian Schulz
Jonathan Melin
Peter Rehling
Piotr Neumann
Ralf Ficner
P2860
P304
P356
10.1083/JCB.201105098
P407
P577
2011-11-07T00:00:00Z