Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway - Test2 - elhamkhani - TriplyDB

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

http://www.wikidata.org/entity/Q35670711

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pH sensing and regulation in cancer Ion channels and transporters in tumour cell migration and invasion The interplay between the proteolytic, invasive, and adhesive domains of invadopodia and their roles in cancer invasion Invadopodia in context Podoplanin mediates ECM degradation by squamous carcinoma cells through control of invadopodia stability Electrochemical regulation of budding yeast polarity Multiparametric classification links tumor microenvironments with tumor cell phenotype Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells Considering protonation as a posttranslational modification regulating protein structure and function.SRChing for the substrates of Src.Macrophage contact induces RhoA GTPase signaling to trigger tumor cell intravasation.Invadosomes in their natural habitat.The Nck-interacting kinase NIK increases Arp2/3 complex activity by phosphorylating the Arp2 subunit Mechanical interplay between invadopodia and the nucleus in cultured cancer cells PDGFRα signaling in the primary cilium regulates NHE1-dependent fibroblast migration via coordinated differential activity of MEK1/2-ERK1/2-p90RSK and AKT signaling pathways 5'-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion.Validation of a device for the active manipulation of the tumor microenvironment during intravital imaging.Breaking away: matrix remodeling from the leading edge.Prolactin Signaling Stimulates Invasion via Na(+)/H(+) Exchanger NHE1 in T47D Human Breast Cancer Cells Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis.Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis.Regulation of invadopodia by the tumor microenvironment.Microenvironmental acidosis in carcinogenesis and metastases: new strategies in prevention and therapy.ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion Profilin1 regulates invadopodium maturation in human breast cancer cells Abl2/Abl-related gene stabilizes actin filaments, stimulates actin branching by actin-related protein 2/3 complex, and promotes actin filament severing by cofilin.Bioengineering paradigms for cell migration in confined microenvironments.Potential crosstalk between cofilin-1 and EGFR pathways in cisplatin resistance of non-small-cell lung cancer Mast Cell Proteases 6 and 7 Stimulate Angiogenesis by Inducing Endothelial Cells to Release Angiogenic Factors.N-WASP-mediated invadopodium formation is involved in intravasation and lung metastasis of mammary tumors Cyclase-associated protein (CAP) acts directly on F-actin to accelerate cofilin-mediated actin severing across the range of physiological pH.Src binds cortactin through an SH2 domain cystine-mediated linkage.Actin-interacting Protein 1 Promotes Disassembly of Actin-depolymerizing Factor/Cofilin-bound Actin Filaments in a pH-dependent Manner.β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation.pHocal adhesion kinase regulation is on a FERM foundation.Endosomal acidification by Na+/H+ exchanger NHE5 regulates TrkA cell-surface targeting and NGF-induced PI3K signaling.Mena(INV) dysregulates cortactin phosphorylation to promote invadopodium maturation.Soft matrix is a natural stimulator for cellular invasiveness.Imaging interactions between macrophages and tumour cells that are involved in metastasis in vivo and in vitro.Directed cell invasion and migration during metastasis.

P2860

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P2860

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

http://www.wikidata.org/entity/Q35670711

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

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Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

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type

label

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

@ast

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

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prefLabel

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

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Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

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P1433

Journal of Cell Biology

P1476

Cortactin phosphorylation regulates cell invasion through a pH-dependent pathway

@en

P2093

Anthony J Koleske

http://www.w3.org/2001/XMLSchema#string

Christopher C Mader

http://www.w3.org/2001/XMLSchema#string

Hava Gil-Henn

http://www.w3.org/2001/XMLSchema#string

John Condeelis

http://www.w3.org/2001/XMLSchema#string

Jose Javier Bravo-Cordero

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Matthew Oser

http://www.w3.org/2001/XMLSchema#string

Xiaoming Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Activation of Arp2/3 complex-mediated actin polymerization by cortactin

The actin-bundling protein fascin stabilizes actin in invadopodia and potentiates protrusive invasion

A role for the podosome/invadopodia scaffold protein Tks5 in tumor growth in vivo

Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization

Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

Cortactin localization to sites of actin assembly in lamellipodia requires interactions with F-actin and the Arp2/3 complex.

Actin depolymerizing factor (ADF/cofilin) enhances the rate of filament turnover: implication in actin-based motility

Direct binding of the Na--H exchanger NHE1 to ERM proteins regulates the cortical cytoskeleton and cell shape independently of H(+) translocation

The Nck-interacting kinase (NIK) phosphorylates the Na+-H+ exchanger NHE1 and regulates NHE1 activation by platelet-derived growth factor

Cortactin: coupling membrane dynamics to cortical actin assembly

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903-920

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10.1083/JCB.201103045

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5

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195

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Daniel R Larson

Marco A O Magalhães

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2011-11-21T00:00:00Z

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51820016

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22105349

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phosphorylation

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3257566

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