Challenges of translating basic research into therapeutics: resveratrol as an example
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Resveratrol and clinical trials: the crossroad from in vitro studies to human evidenceCurcumin and Resveratrol as Promising Natural Remedies with Nanomedicine Approach for the Effective Treatment of Triple Negative Breast CancerAn Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of ResveratrolNatural compounds as anticancer agents: Experimental evidenceThe search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individualsTargeting Nitric Oxide with Natural Derived Compounds as a Therapeutic Strategy in Vascular DiseasesEvaluation of a Mathematical Model of Rat Body Weight Regulation in Application to Caloric Restriction and Drug Treatment StudiesResveratrol in metabolic health: an overview of the current evidence and perspectives.Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus--systematic review and meta-analysis.Pharmacologic Means of Extending Lifespan.Resveratrol induces long-lasting IL-8 expression and peculiar EGFR activation/distribution in human keratinocytes: mechanisms and implications for skin administration.The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in miceResveratrol encapsulated in novel fusogenic liposomes activates Nrf2 and attenuates oxidative stress in cerebromicrovascular endothelial cells from aged rats.Resveratrol and para-coumarate serve as ring precursors for coenzyme Q biosynthesis.The journey of resveratrol from yeast to human.Disruption of Nrf2 signaling impairs angiogenic capacity of endothelial cells: implications for microvascular aging.Antitumor activity of melinjo (Gnetum gnemon L.) seed extract in human and murine tumor models in vitro and in a colon-26 tumor-bearing mouse model in vivo.Are sirtuins viable targets for improving healthspan and lifespan?Unique vascular protective properties of natural products: supplements or future main-line drugs with significant anti-atherosclerotic potential?Critical review of resveratrol in xenobiotic-induced hepatotoxicity.Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment.Exploring the promise of resveratrol: where do we go from here?Pilot study of resveratrol in older adults with impaired glucose tolerance.A healthier approach to clinical trials evaluating resveratrol for primary prevention of age‐related diseases in healthy populations.Empirical verification of evolutionary theories of aging.Resveratrol and health--a comprehensive review of human clinical trials.Natural compounds with anti-ageing activity.Resveratrol and its oligomers: modulation of sphingolipid metabolism and signaling in disease.Hepatoprotective properties of extensively studied medicinal plant active constituents: possible common mechanisms.Antihyperuricemic and nephroprotective effects of resveratrol and its analogues in hyperuricemic mice.Resveratrol supplementation: Where are we now and where should we go?Significance of Resveratrol in Clinical Management of Chronic Diseases.Prophylactic supplementation of resveratrol is more effective than its therapeutic use against doxorubicin induced cardiotoxicity.Sauces, spices, and condiments: definitions, potential benefits, consumption patterns, and global markets.Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target.Resveratrol derivatives as a pharmacological tool.Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice.Resveratrol modulates the angiogenic response to exercise training in skeletal muscles of aged men.Regulation by resveratrol of the cellular factors mediating liver damage and regeneration after acute toxic liver injury.
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Challenges of translating basic research into therapeutics: resveratrol as an example
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Challenges of translating basic research into therapeutics: resveratrol as an example
@ast
Challenges of translating basic research into therapeutics: resveratrol as an example
@en
type
label
Challenges of translating basic research into therapeutics: resveratrol as an example
@ast
Challenges of translating basic research into therapeutics: resveratrol as an example
@en
prefLabel
Challenges of translating basic research into therapeutics: resveratrol as an example
@ast
Challenges of translating basic research into therapeutics: resveratrol as an example
@en
P2093
P2860
P50
P356
P1476
Challenges of translating basic research into therapeutics: resveratrol as an example
@en
P2093
James M Smoliga
Joseph A Baur
P2860
P304
P356
10.1093/GERONA/GLR062
P407
P577
2011-07-11T00:00:00Z