Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
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EMT-Inducing Molecular Factors in Gynecological CancersGAB2--a scaffolding protein in cancerStructure and function of Gab2 and its role in cancer (Review)K+ Channel Inhibition Differentially Regulates Migration of Intestinal Epithelial Cells in Inflamed vs. Non-Inflamed Conditions in a PI3K/Akt-Mediated MannerOncogenic Signaling Adaptor ProteinsRegulation of the Epithelial-Mesenchymal Transition by Claudin-3 and Claudin-4Elevated Gab2 induces tumor growth and angiogenesis in colorectal cancer through upregulating VEGF levelsMicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancerExpression of signaling adaptor proteins predicts poor prognosis in pancreatic ductal adenocarcinoma.ADP-ribosylation factor-like 4C (ARL4C), a novel ovarian cancer metastasis suppressor, identified by integrated genomics.Gab2 is a novel prognostic factor for colorectal cancer patientsEpithelial-mesenchymal transition in ovarian carcinomaGrb2-associated binder 2 silencing impairs growth and migration of H1975 cells via modulation of PI3K-Akt signaling.Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancerGrb2-associated binder-2 gene promotes migration of non-small cell lung cancer cells via Akt signaling pathway.Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression.Epithelial-mesenchymal transition enhances nanoscale actin filament dynamics of ovarian cancer cells.SHP-2-upregulated ZEB1 is important for PDGFRα-driven glioma epithelial-mesenchymal transition and invasion in mice and humans.In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene.Reverse-phase protein array analysis to identify biomarker proteins in human pancreatic cancer.The regulatory roles of phosphatases in cancer.Gab2 mediates hepatocellular carcinogenesis by integrating multiple signaling pathways.Grb2-associated binder 2 expression and its roles in uveal melanoma invasion.YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway.MiR125a-5p acting as a novel Gab2 suppressor inhibits invasion of glioma.Clinical significance of GAB2, a scaffolding/docking protein acting downstream of EGFR in human colorectal cancer.Major chromosomal breakpoint intervals in breast cancer co-localize with differentially methylated regionsGAB2 Amplification in Squamous Cell Lung Cancer of Non-Smokers.Shp2 regulates migratory behavior and response to EGFR-TKIs through ERK1/2 pathway activation in non-small cell lung cancer cells.ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis.BRAF inhibition upregulates a variety of receptor tyrosine kinases and their downstream effector Gab2 in colorectal cancer cell lines.Cooperative interaction of hepatocyte growth factor and neuregulin regulates Schwann cell migration and proliferation through Grb2-associated binder-2 in peripheral nerve repair.Effects of Grb2-associated binding protein 2-specific siRNA on the migration and invasion of MG-63 osteosarcoma cells.
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P2860
Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@ast
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@en
type
label
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@ast
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
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prefLabel
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@ast
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@en
P2093
P2860
P356
P1433
P1476
Gab2 regulates the migratory b ...... athway in ovarian cancer cells
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2011.435
P407
P577
2011-09-26T00:00:00Z