Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
about
Links between metabolism and cancerEvolutionary acquisition of cysteines determines FOXO paralog-specific redox signaling.Ribosomal proteins and human diseases: pathogenesis, molecular mechanisms, and therapeutic implicationsActivation of caspases and inhibition of ribosome biogenesis mediate antitumor activity of Chijongdan in A549 non-small lung cancer cells.Forkhead Box M1 Is Essential for Nuclear Localization of Glioma-associated Oncogene Homolog 1 in Glioblastoma Multiforme Cells by Promoting Importin-7 Expression.Expression, function, and targeting of the nuclear exporter chromosome region maintenance 1 (CRM1) protein.Emphasising the European Union's Commitment to Cancer Research: a helicopter view of the Seventh Framework Programme for Research and Technological Development.Nuclear import of the thyroid hormone receptor α1 is mediated by importin 7, importin β1, and adaptor importin α1Functional impact bias reveals cancer drivers.Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stressMelatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells.The ATPase hCINAP regulates 18S rRNA processing and is essential for embryogenesis and tumour growth.Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolismCRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications.miR-661 downregulates both Mdm2 and Mdm4 to activate p53.Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival.Extensive cargo identification reveals distinct biological roles of the 12 importin pathways.Scission of the p53-MDM2 Loop by Ribosomal Proteins.p53 -Dependent and -Independent Nucleolar Stress Responses.p53 and ribosome biogenesis stress: the essentials.Biological significance of the importin-β family-dependent nucleocytoplasmic transport pathways.Selective inhibitors of nuclear export (SINE)--a novel class of anti-cancer agents.Census and evaluation of p53 target genes.Involvement of chromosome region maintenance 1 (CRM1) in the formation and progression of esophageal squamous cell carcinoma.USP10 antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation.Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex.XPO1 in B cell hematological malignancies: from recurrent somatic mutations to targeted therapy.Identification of ribosomal protein S25 (RPS25)-MDM2-p53 regulatory feedback loop.C9orf72 is differentially expressed in the central nervous system and myeloid cells and consistently reduced in C9orf72, MAPT and GRN mutation carriers.PIM1 destabilization activates a p53-dependent response to ribosomal stress in cancer cellsKaryopherins in cancer.Proapoptotic Requirement of Ribosomal Protein L11 in Ribosomal Stress-Challenged Cortical Neurons.Therapeutic vulnerability of multiple myeloma to MIR17PTi, a first-in-class inhibitor of pri-miR-17-92
P2860
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P2860
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@ast
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@en
type
label
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@ast
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@en
prefLabel
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@ast
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@en
P2093
P2860
P1433
P1476
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
@en
P2093
Debora Rosa Bublik
Kristina Grabusic
Lior Golomb
Moshe Oren
Reinat Nevo
Sinisa Volarevic
Sylvia Wilder
Vladimir Kiss
P2860
P304
P356
10.1016/J.MOLCEL.2011.11.022
P577
2012-01-01T00:00:00Z