Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
about
Is the molten globule a third phase of proteins?Tripeptide analysis of protein structures.Synthesis and NMR solution structure of an α-helical hairpin stapled with two disulfide bridgesAccommodation of a highly symmetric core within a symmetric protein superfoldComputer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet DesignFolding of beta pep-4 beta-sheet sandwich dimers and tetramers is influenced by aliphatic hydrophobic residues at the intersubunit interfaceA self-consistent knowledge-based approach to protein designDesign, synthesis, and characterization of a novel hemoproteinTruncation of a β-barrel scaffold dissociates intrinsic stability from its propensity to aggregation.Topological diversity of artificial beta-barrels in water.Novel folded protein domains generated by combinatorial shuffling of polypeptide segments.Sequence replacements in the central beta-turn of plastocyaninThe Framework of Computational Protein Design.Achievements and Challenges in Computational Protein Design.Protein design automation.De novo design of the hydrophobic core of ubiquitin.Synthetic protein design: construction of a four-stranded beta-sheet structure and evaluation of its integrity in methanol-water systems.Knowledge-based potential defined for a rotamer library to design protein sequences.Macrocyclic beta-sheet peptides that mimic protein quaternary structure through intermolecular beta-sheet interactions.De novo design: backbone conformational constraints in nucleating helices and beta-hairpins.Symmetry of Fv architecture is conducive to grafting a second antibody binding site in the Fv region.Computer simulations of de novo designed helical proteins.GeneDesign: rapid, automated design of multikilobase synthetic genes.De novo design of beta-sheet proteins.Rational design of nascent metalloenzymesConversion of a maltose receptor into a zinc biosensor by computational design.Rational protein design: combining theory and experiment.The Alacoil: a very tight, antiparallel coiled-coil of helices.What makes a protein a protein? Hydrophobic core designs that specify stability and structural properties.Solution structure of alpha t alpha, a helical hairpin peptide of de novo designA de novo redesign of the WW domainEnhancement of essential amino acid contents in crops by genetic engineering and protein design.De novo design of the hydrophobic cores of proteins.A recipe for designing water-soluble, beta-sheet-forming peptides.Artificial beta-sheets: chemical models of beta-sheets.Recognition of synthetic glycopeptides by HIV-1 broadly neutralizing antibodies and their unmutated ancestors.Energy functions in de novo protein design: current challenges and future prospects.A designed beta-hairpin peptide in crystalsEngineering of betabellin-15D: a 64 residue beta sheet protein that forms long narrow multimeric fibrils.A folding pathway for betapep-4 peptide 33mer: from unfolded monomers and beta-sheet sandwich dimers to well-structured tetramers.
P2860
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P2860
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@ast
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@en
type
label
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@ast
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@en
prefLabel
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@ast
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@en
P2093
P2860
P356
P1476
Betadoublet: de novo design, synthesis, and characterization of a beta-sandwich protein.
@en
P2093
D C Richardson
J S Richardson
N B Tweedy
R W Williams
P2860
P304
P356
10.1073/PNAS.91.19.8747
P407
P577
1994-09-01T00:00:00Z