Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death
about
Posttranslational modification and regulation of glutamate-cysteine ligase by the α,β-unsaturated aldehyde 4-hydroxy-2-nonenalGlutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosisStructure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligaseManipulation of cellular GSH biosynthetic capacity via TAT-mediated protein transduction of wild-type or a dominant-negative mutant of glutamate cysteine ligase alters cell sensitivity to oxidant-induced cytotoxicityRegulation of glutathione synthesisGlutathione synthesisRegulation of cell survival and death by pyridine nucleotidesResponses of Nontransformed Human Hepatocytes to Conditional Expression of Full-Length Hepatitis C Virus Open Reading FrameAdenoviral overexpression of the glutamylcysteine ligase catalytic subunit protects pancreatic islets against oxidative stressMechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesisRapid activation of glutamate cysteine ligase following oxidative stress.Enhanced glutathione biosynthetic capacity promotes resistance to As3+-induced apoptosis.Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.An ethnic-specific polymorphism in the catalytic subunit of glutamate-cysteine ligase impairs the production of glutathione intermediates in vitro.Stereoselective effects of 4-hydroxynonenal in cultured mouse hepatocytes.Emerging regulatory paradigms in glutathione metabolism.Glutathione efflux and cell death.Sex-specific molecular genetic response to UVB exposure in Xiphophorus maculatus skin.Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish.Decreased zinc availability affects glutathione metabolism in neuronal cells and in the developing brain.Low-level domoic acid protects mouse cerebellar granule neurons from acute neurotoxicity: role of glutathioneEffect of polyI:C cotreatment on halothane-induced liver injury in miceDistinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.Follicle-stimulating hormone and estradiol interact to stimulate glutathione synthesis in rat ovarian follicles and granulosa cells.Proteomic analysis of the secretome of porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus.Tumor necrosis factor-associated protein 1 (TRAP-1) protects cells from oxidative stress and apoptosis.Molecular mechanism(s) for UV-B irradiation-induced glutathione depletion in cultured human keratinocytes.Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells.Differences in lung glutathione metabolism may account for rodent susceptibility in elastase-induced emphysema development.Alteration in glutathione homeostasis and oxidative stress during the sequelae of trimethyltin syndrome in rat brain.Defective DNA strand break repair causes chromosomal instability and accelerates liver carcinogenesis in mice.Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice.SLCO/OATP-like transport of glutathione in FasL-induced apoptosis: glutathione efflux is coupled to an organic anion exchange and is necessary for the progression of the execution phase of apoptosis.
P2860
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P2860
Caspase-3-Dependent Cleavage of the Glutamate-L-Cysteine Ligase Catalytic Subunit during Apoptotic Cell Death
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@ast
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@en
type
label
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@ast
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@en
prefLabel
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@ast
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@en
P2093
P2860
P1476
Caspase-3-Dependent Cleavage o ...... it during Apoptotic Cell Death
@en
P2093
Cecile M Krejsa
Christopher C Franklin
Collin C White
Nelson Fausto
Robert H Pierce
Terrance J Kavanagh
P2860
P304
P356
10.1016/S0002-9440(10)61135-2
P407
P577
2002-05-01T00:00:00Z