Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation. - Test2 - elhamkhani - TriplyDB

Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.

Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.

http://www.wikidata.org/entity/Q35751997

about

Molecular Correlates and Recent Advancements in the Diagnosis and Screening of FMR1-Related Disorders Detection and Quantification of the Fragile X Mental Retardation Protein 1 (FMRP)Modeling Fragile X Syndrome Using Human Pluripotent Stem Cells From FMRP function to potential therapies for fragile X syndrome.Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders CGG repeat in the FMR1 gene: size matters Mouse models of fragile X-associated tremor ataxia.Fibroblast phenotype in male carriers of FMR1 premutation alleles CNS expression of murine fragile X protein (FMRP) as a function of CGG-repeat size.Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome.iPSC-derived forebrain neurons from FXS individuals show defects in initial neurite outgrowth Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans.Clinical and molecular implications of mosaicism in FMR1 full mutations.Cerebral protein synthesis in a knockin mouse model of the fragile X premutation.Premutation CGG-repeat expansion of the Fmr1 gene impairs mouse neocortical development.Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome.Ubiquitin-positive intranuclear inclusions in neuronal and glial cells in a mouse model of the fragile X premutation.Mouse models of the fragile x premutation and the fragile X associated tremor/ataxia syndrome.The FMR1 gene and fragile X-associated tremor/ataxia syndrome.Microsatellite repeat instability and neurological disease.A mouse model of the fragile X premutation: effects on behavior, dendrite morphology, and regional rates of cerebral protein synthesis.The fragile x mental retardation syndrome 20 years after the FMR1 gene discovery: an expanding universe of knowledge.Altered hypothalamus-pituitary-adrenal gland axis regulation in the expanded CGG-repeat mouse model for fragile X-associated tremor/ataxia syndrome.Widespread non-central nervous system organ pathology in fragile X premutation carriers with fragile X-associated tremor/ataxia syndrome and CGG knock-in mice.FMR1 premutation and full mutation molecular mechanisms related to autism.Regional FMRP deficits and large repeat expansions into the full mutation range in a new Fragile X premutation mouse model Clustered burst firing in FMR1 premutation hippocampal neurons: amelioration with allopregnanolone.Induced expression of expanded CGG RNA causes mitochondrial dysfunction in vivo Presence of inclusions positive for polyglycine containing protein, FMRpolyG, indicates that repeat-associated non-AUG translation plays a role in fragile X-associated primary ovarian insufficiency.Early mitochondrial abnormalities in hippocampal neurons cultured from Fmr1 pre-mutation mouse model.Distribution and frequency of intranuclear inclusions in female CGG KI mice modeling the fragile X premutation Monogenic mouse models of autism spectrum disorders: Common mechanisms and missing links.Enhanced asynchronous Ca(2+) oscillations associated with impaired glutamate transport in cortical astrocytes expressing Fmr1 gene premutation expansion Epigenetics in nucleotide repeat expansion disorders.Dnmt1 deficiency promotes CAG repeat expansion in the mouse germline Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency.CGG-repeat length and neuropathological and molecular correlates in a mouse model for fragile X-associated tremor/ataxia syndrome.The cyclic AMP phenotype of fragile X and autism The quadruplex r(CGG)n destabilizing cationic porphyrin TMPyP4 cooperates with hnRNPs to increase the translation efficiency of fragile X premutation mRNA

P2860

Q28077980-60C64080-C810-4C14-8563-2C85ABE03C0E Q28079967-18EC6369-E18E-4515-AC7E-990419C4545A Q28080022-F8F31F0C-CFD8-479D-BF03-81585CAA3153 Q30410502-7A92D97F-462A-43A7-B753-122ECC1E2485 Q30458768-C59AA219-B70A-44F0-9A15-B312F9D95FEE Q30464036-4EA5D0E5-6E56-4409-A5AE-B0CBD5250812 Q33477843-950D0688-CAFD-4300-A90F-78261302F80E Q33552176-38555869-DE05-4DCA-9594-645ED4971004 Q33649307-49271733-54B4-46D2-9EE4-E0761732BD41 Q33775485-82ED4F12-B86F-484F-A1F7-736484BB44F0 Q33919340-A999884C-0D97-4AB9-A936-AF1C7F2F41AA Q34055453-1065EEB3-1505-4C27-85CE-B18B8F94FC86 Q34074523-03A7FE98-BFB7-45D1-9493-7C8909803A4F Q34198878-D9267D0D-7E0E-4EC7-8229-511BC6206DC6 Q34295112-9C311FB4-56F2-47B4-A23E-709B1C1CD3B2 Q34399389-1C1AFAF0-1EFC-41E8-A942-986C9C935A99 Q34407383-BA2D0804-FEA4-4140-8819-0B7953C011B1 Q34915612-67A7B3E0-6FC9-41B5-B879-64A263D63F22 Q35037764-A0FE0B28-0480-42B8-82AE-5008ECF9FDC3 Q35061671-060A2D16-B101-4387-83F9-08BEDCC42A31 Q35064141-1A6F2161-74CC-4E0B-813B-C575FBAB68CD Q35148962-6EE7259B-47D9-46C7-89A0-F94DB9478A1D Q35170163-761B3BBA-9E7D-4497-BD35-0A3BF197EB87 Q35533280-8EB4159F-A309-4EA7-9FE3-F6538ED69FD6 Q35567307-67BD702F-F220-4AE3-AAE4-5464B6713DBE Q35680720-D28757B5-67B3-4CD7-B212-42943A858969 Q35944748-E4EB5CD9-B9E5-4810-84E3-89E8C241CD92 Q36026897-5FA28EC9-F835-421A-8316-AEC81A533D8C Q36188438-A4F9E79B-7772-42C7-8913-25B648543270 Q36368705-0457FCC9-EC2C-4EBC-BBFC-16721D8D5800 Q36588189-391E227C-A361-4022-B45E-037BEE3425E4 Q36611172-CF493AE2-AC51-432A-8D7B-D20664D55ACD Q36716971-F5919BE9-A40F-483D-9E26-9E54F654EE95 Q36832709-8A5630BD-E43C-4E0C-A8BF-F87F592BD64A Q36848454-9EDB43E3-435F-4C62-8952-F0CC0669F287 Q36939612-34CEABC2-82A0-431F-B0EE-04804D7840C2 Q36946491-C9084577-9032-4531-84E0-4DA2A5CA99C1 Q37021134-BF8F9161-96E4-40B4-A489-FF21AACB5CBA Q37097136-4CEEFDE3-BB2D-404A-AE9F-3A5EBE93D97A Q37181553-6B59411B-C405-4387-BF9E-EA1F8E539E52

P2860

Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.

http://www.wikidata.org/entity/Q35751997

description

2006 nî lūn-bûn

@nan

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

2006年论文

@zh

2006年论文

@zh-cn

name

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@ast

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@en

type

label

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@ast

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@en

prefLabel

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@ast

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@en

P1433

Q35751997-5825858D-12CD-4FA4-BBD4-973E76613B9A

P1476

Q35751997-8E8EBD2F-E266-479A-A8E1-C6ABCC09FFB7

P2093

Q35751997-28422174-DF4B-4C3D-9E79-34FAD207DC87

Q35751997-3918BFF0-EC53-4C4E-B847-8F437290653A

Q35751997-5AF23DEF-D391-42A4-8041-4CA897D6BCC1

Q35751997-7BEB41E4-5684-4ECE-AB61-98C6C52680C4

Q35751997-8785C10C-DCEC-4878-8AE3-B90E483670A2

Q35751997-A135BE93-B40C-4A59-A710-B6ADF1C7BBBF

Q35751997-E215AF7D-856F-4089-81E4-C64A5EB75BF6

Q35751997-E4B9CAD6-2C39-4A3B-BB76-B8137A41A51B

Q35751997-F0F15BDF-FF82-408C-8A81-748EFE3FFE6D

P2860

Q35751997-03B2FCA6-BBC3-4736-8F47-4231C5496C0B

Q35751997-09BA2151-F542-41A3-8751-CD9748FCCD93

Q35751997-0A680763-B5E2-4B20-BEF2-1174B849B47F

Q35751997-0B60C933-58AA-48F8-A2EC-5AB6B59CDA1C

Q35751997-0E45732E-5032-4FE9-9BB8-297EFE6B178E

Q35751997-1A6CDC5A-453F-40C1-A346-F5DBAC7AB1B1

Q35751997-1B0CF1B1-4FFC-4DEC-A8D2-1117B0E0DDFB

Q35751997-26A0B892-E56C-4B98-A7CF-CC23B72A4B01

Q35751997-2AFE8F93-CBCA-4B2F-A017-6478C9FC8E70

Q35751997-33DE7E26-207C-4AFC-AEFD-D95EED69ABF2

P304

Q35751997-1F5535C7-E170-4761-AB09-C301FD0F2D29

P31

Q35751997-7437CEFC-1B9F-4DC5-91A1-359BF58E01DE

P356

Q35751997-489B58A8-AA08-4479-A8AF-D7C549F1D409

P407

Q35751997-FAB920E0-084E-41D2-8533-6D388A0E3B9C

P433

Q35751997-02B9B840-EEED-4FC6-A3E7-3813F3572782

P478

Q35751997-F77E3034-C4AA-474D-8CA5-6E2B3AB97A7B

P577

Q35751997-025A6411-20E2-47D9-BC3A-958ED881F9B3

P5875

Q35751997-5A9E3B04-AC4C-4322-B82E-296FE7CC37CA

P698

Q35751997-918355FA-5A92-48A3-A513-3DA6B813A020

P932

Q35751997-782D687E-B58D-4440-8A76-A04528BB9EB5

P356

J.YEXCR.2006.10.002

P1433

Experimental Cell Research

P1476

Elevated Fmr1 mRNA levels and ...... lated Fragile X full mutation.

@en

P2093

B A Oostra

http://www.w3.org/2001/XMLSchema#string

C E Bakker

http://www.w3.org/2001/XMLSchema#string

D L Nelson

http://www.w3.org/2001/XMLSchema#string

E J Mientjes

http://www.w3.org/2001/XMLSchema#string

H C Van der Linde

http://www.w3.org/2001/XMLSchema#string

I M Nieuwenhuizen

http://www.w3.org/2001/XMLSchema#string

J R Brouwer

http://www.w3.org/2001/XMLSchema#string

L A Severijnen

http://www.w3.org/2001/XMLSchema#string

R Willemsen

http://www.w3.org/2001/XMLSchema#string

P2860

Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis

Expansion of the fragile X CGG repeat in females with premutation or intermediate alleles

Variation of the CGG repeat at the fragile X site results in genetic instability: resolution of the Sherman paradox

Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome

Visual experience regulates transient expression and dendritic localization of fragile X mental retardation protein

Cognitive decline, neuromotor and behavioural disturbances in a mouse model for fragile-X-associated tremor/ataxia syndrome (FXTAS).

Active demethylation of the paternal genome in the mouse zygote.

Premature ovarian failure among fragile X premutation carriers: parent-of-origin effect?

Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in the fragile-X syndrome.

P304

244-253

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.YEXCR.2006.10.002

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

313

http://www.w3.org/2001/XMLSchema#string

P577

2006-10-13T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6649609

http://www.w3.org/2001/XMLSchema#string

P698

17150213

http://www.w3.org/2001/XMLSchema#string

P932

1852528

http://www.w3.org/2001/XMLSchema#string