Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.
about
Molecular insights into the premature aging disease progeriaNuclear lamins and oxidative stress in cell proliferation and longevityDegradation-mediated protein quality control at the inner nuclear membranePotential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria-related disordersRecent advances in understanding the role of lamins in health and diseasePhysiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgePotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesTemsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular PhenotypeThe effect of the lamin A and its mutants on nuclear structure, cell proliferation, protein stability, and mobility in embryonic cellsPrelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cellHP1α mediates defective heterochromatin repair and accelerates senescence in Zmpste24-deficient cells.Rapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamicsSulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts.Identifying pathological biomarkers: histochemistry still ranks high in the omics era.Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteinsA filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction.All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.On the future contents of a small journal of histochemistry.Arterial ageing.Muscle development, regeneration and laminopathies: how lamins or lamina-associated proteins can contribute to muscle development, regeneration and disease.Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes.Antisense-Based Progerin Downregulation in HGPS-Like Patients' Cells.Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells.Skeletal muscle features in myotonic dystrophy and sarcopenia: do similar nuclear mechanisms lead to skeletal muscle wasting?Nuclear damages and oxidative stress: new perspectives for laminopathies.The nuclear lamina in health and disease.Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations.Nucleolar expansion and elevated protein translation in premature aging.Histochemistry as an irreplaceable approach for investigating functional cytology and histology.Autophagic Removal of Farnesylated Carboxy-Terminal Lamin Peptides.An overview of treatment strategies for Hutchinson-Gilford Progeria syndrome.Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells.
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P2860
Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@ast
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@en
type
label
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@ast
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@en
prefLabel
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@ast
Autophagic degradation of farn ...... oach to lamin-linked progeria.
@en
P2093
P2860
P50
P356
P1476
Autophagic degradation of farn ...... roach to lamin-linked progeria
@en
P2093
M Ortolani
M R D'Apice
N M Maraldi
S Prencipe
P2860
P356
10.4081/EJH.2011.E36
P50
P577
2011-10-19T00:00:00Z