The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.
about
The transcription factor p53: not a repressor, solely an activatorThe CHR site: definition and genome-wide identification of a cell cycle transcriptional elementThe p53-p21-DREAM-CDE/CHR pathway regulates G2/M cell cycle genesCell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs.Human papilloma virus E7 oncoprotein abrogates the p53-p21-DREAM pathway.dREAM co-operates with insulator-binding proteins and regulates expression at divergently paired genes.The DREAM complex: master coordinator of cell cycle-dependent gene expression.Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases.p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes.Activation of JNK contributes to evodiamine-induced apoptosis and G2/M arrest in human colorectal carcinoma cells: a structure-activity study of evodiamineStructural mechanisms of DREAM complex assembly and regulation.OGFOD1 is required for breast cancer cell proliferation and is associated with poor prognosis in breast cancerRBF binding to both canonical E2F targets and noncanonical targets depends on functional dE2F/dDP complexesRole of dual specificity tyrosine-phosphorylation-regulated kinase 1B (Dyrk1B) in S-phase entry of HPV E7 expressing cells from quiescenceThe forkhead transcription factor FOXM1 controls cell cycle-dependent gene expression through an atypical chromatin binding mechanism.NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors.Structural basis for LIN54 recognition of CHR elements in cell cycle-regulated promotersIntegration of TP53, DREAM, MMB-FOXM1 and RB-E2F target gene analyses identifies cell cycle gene regulatory networks.SWIM: a computational tool to unveiling crucial nodes in complex biological networks.Human papillomavirus type 16 E7 perturbs DREAM to promote cellular proliferation and mitotic gene expression.Indirect p53-dependent transcriptional repression of Survivin, CDC25C, and PLK1 genes requires the cyclin-dependent kinase inhibitor p21/CDKN1A and CDE/CHR promoter sites binding the DREAM complex.MYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis.Minute Virus of Mice Inhibits Transcription of the Cyclin B1 Gene during Infection.Central spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapyP53 suppresses ribonucleotide reductase via inhibiting mTORC1.Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control.Polo-like kinase 4 transcription is activated via CRE and NRF1 elements, repressed by DREAM through CDE/CHR sites and deregulated by HPV E7 protein.The Drosophila LIN54 homolog Mip120 controls two aspects of oogenesis.The DREAM complex through its subunit Lin37 cooperates with Rb to initiate quiescence.Cscan: finding common regulators of a set of genes by using a collection of genome-wide ChIP-seq datasetsp53 can repress transcription of cell cycle genes through a p21(WAF1/CIP1)-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.Simplify p53: just an activator.Interchanging heads: p53 re-composes the DREAM/MMB complex to repress transcription.Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes.Timing of transcription during the cell cycle: Protein complexes binding to E2F, E2F/CLE, CDE/CHR, or CHR promoter elements define early and late cell cycle gene expression.Cell cycle arrest through indirect transcriptional repression by p53: I have a DREAM.Virtual Sorting Has a Distinctive Advantage in Identification of Anticorrelated Genes and Further Negative Regulators of Immune Cell Subpopulations.Cell cycle transcription control: DREAM/MuvB and RB-E2F complexes.The Temporal Regulation of S Phase Proteins During G1.MuvB: A Key to Cell Cycle Control in Ovarian Cancer.
P2860
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P2860
The CHR promoter element controls cell cycle-dependent gene transcription and binds the DREAM and MMB complexes.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@ast
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@en
type
label
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@ast
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@en
prefLabel
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@ast
The CHR promoter element contr ...... s the DREAM and MMB complexes.
@en
P2093
P2860
P50
P356
P1476
The CHR promoter element contr ...... ds the DREAM and MMB complexes
@en
P2093
Eberhard Krause
James A DeCaprio
Marianne Quaas
Megha Padi
Michael Schümann
P2860
P304
P356
10.1093/NAR/GKR793
P407
P577
2011-11-07T00:00:00Z