Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo
about
CD69 expression potentially predicts response to bendamustine and its modulation by ibrutinib or idelalisib enhances cytotoxic effect in chronic lymphocytic leukemia.CpG oligodeoxynucleotide CpG-685 upregulates functional interleukin-21 receptor on chronic lymphocytic leukemia B cells through an NF-κB mediated pathwayMicroenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment.Modulation of B-cell receptor and microenvironment signaling by a guanine exchange factor in B-cell malignanciesTargeting antigen-independent proliferation in chronic lymphocytic leukemia through differential kinase inhibition.Modeling the chronic lymphocytic leukemia microenvironment in vitro.Mechanisms of Resistance to Targeted Therapies in Chronic Lymphocytic Leukemia.Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia.Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment.Mixed-species RNAseq analysis of human lymphoma cells adhering to mouse stromal cells identifies a core gene set that is also differentially expressed in the lymph node microenvironment of mantle cell lymphoma and chronic lymphocytic leukemia patienIFI16 reduced expression is correlated with unfavorable outcome in chronic lymphocytic leukemia.Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration.A novel ex vivo high-throughput assay reveals antiproliferative effects of idelalisib and ibrutinib in chronic lymphocytic leukemia.Microenvironmental agonists generate phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL
P2860
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P2860
Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Co-culture of primary CLL cell ...... to those proliferating in vivo
@ast
Co-culture of primary CLL cell ...... to those proliferating in vivo
@en
type
label
Co-culture of primary CLL cell ...... to those proliferating in vivo
@ast
Co-culture of primary CLL cell ...... to those proliferating in vivo
@en
prefLabel
Co-culture of primary CLL cell ...... to those proliferating in vivo
@ast
Co-culture of primary CLL cell ...... to those proliferating in vivo
@en
P2093
P2860
P356
P1433
P1476
Co-culture of primary CLL cell ...... to those proliferating in vivo
@en
P2093
Carles Palacio
Cecilia Carpio
Francesc Bosch
Júlia Carabia
Noelia Purroy
Pau Abrisqueta
P2860
P304
P356
10.18632/ONCOTARGET.2939
P407
P50
P577
2015-04-01T00:00:00Z