Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication.
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Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virusNuclear Magnetic Resonance Structure of the Nucleic Acid-Binding Domain of Severe Acute Respiratory Syndrome Coronavirus Nonstructural Protein 3Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological EvaluationPapain-Like Protease 1 from Transmissible Gastroenteritis Virus: Crystal Structure and Enzymatic Activity toward Viral and Cellular SubstratesStructure of Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Has Implications for Coronavirus nsp1 Function and EvolutionPotent and selective inhibition of pathogenic viruses by engineered ubiquitin variants.Positional-scanning fluorigenic substrate libraries reveal unexpected specificity determinants of DUBs (deubiquitinating enzymes).A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication.Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like protease.Exchange of the coronavirus replicase polyprotein cleavage sites alters protease specificity and processing.Proteasome inhibition in vivo promotes survival in a lethal murine model of severe acute respiratory syndrome.Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.PEGylated substrates of NSP4 protease: A tool to study protease specificity.A G-quadruplex-binding macrodomain within the "SARS-unique domain" is essential for the activity of the SARS-coronavirus replication-transcription complex.Mouse hepatitis virus liver pathology is dependent on ADP-ribose-1''-phosphatase, a viral function conserved in the alpha-like supergroup.Characterization of a critical interaction between the coronavirus nucleocapsid protein and nonstructural protein 3 of the viral replicase-transcriptase complex.Competitive fitness in coronaviruses is not correlated with size or number of double-membrane vesicles under reduced-temperature growth conditions.A new cistron in the murine hepatitis virus replicase gene.Infectious Bronchitis Coronavirus Limits Interferon Production by Inducing a Host Shutoff That Requires Accessory Protein 5b.Arterivirus subgenomic mRNA synthesis and virion biogenesis depend on the multifunctional nsp1 autoprotease.Mutagenesis of the catalytic and cleavage site residues of the hypovirus papain-like proteases p29 and p48 reveals alternative processing and contributions to optimal viral RNA accumulationType III Interferon Restriction by Porcine Epidemic Diarrhea Virus and the Role of Viral Protein nsp1 in IRF1 Signaling.The first complete genome sequences of clinical isolates of human coronavirus 229E
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P2860
Human coronavirus 229E papain-like proteases have overlapping specificities but distinct functions in viral replication.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Human coronavirus 229E papain- ...... unctions in viral replication.
@ast
Human coronavirus 229E papain- ...... unctions in viral replication.
@en
type
label
Human coronavirus 229E papain- ...... unctions in viral replication.
@ast
Human coronavirus 229E papain- ...... unctions in viral replication.
@en
prefLabel
Human coronavirus 229E papain- ...... unctions in viral replication.
@ast
Human coronavirus 229E papain- ...... unctions in viral replication.
@en
P2093
P2860
P50
P356
P1433
P1476
Human coronavirus 229E papain- ...... unctions in viral replication.
@en
P2093
Barbara Schelle
John Ziebuhr
Nadja Karl
Sonja Bayer
P2860
P304
P356
10.1128/JVI.02091-06
P407
P577
2007-01-24T00:00:00Z