Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer
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Genetic determinants and potential therapeutic targets for pancreatic adenocarcinomaA paradigm shift: Cancer therapy with peptide-based B-cell epitopes and peptide immunotherapeutics targeting multiple solid tumor types: Emerging concepts and validation of combination immunotherapyEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.Oxygen in human health from life to death--An approach to teaching redox biology and signaling to graduate and medical studentsCirculating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohortsHypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cellsCastration rapidly decreases local insulin-like growth factor-1 levels and inhibits its effects in the ventral prostate in mice.ENMD-1198, a novel tubulin-binding agent reduces HIF-1alpha and STAT3 activity in human hepatocellular carcinoma(HCC) cells, and inhibits growth and vascularization in vivo.Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer.Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells.Activating transcription factor-3 (ATF3) functions as a tumor suppressor in colon cancer and is up-regulated upon heat-shock protein 90 (Hsp90) inhibitionInsulin-like growth factor-I receptor in proliferation and motility of pancreatic cancer.Inhibition of cancer cell proliferation and metastasis by insulin receptor downregulationFAK and IGF-IR interact to provide survival signals in human pancreatic adenocarcinoma cellsMirk/dyrk1B kinase is upregulated following inhibition of mTOR.Serum IGF-I, IGF-II, IGFBP-3, and IGF-I/IGFBP-3 molar ratio and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trialDifferent patterns of Akt and ERK feedback activation in response to rapamycin, active-site mTOR inhibitors and metformin in pancreatic cancer cells.Combination of anti-IGF-1R antibody A12 and ionizing radiation in upper respiratory tract cancers.Diabetes and pancreatic cancer.Mechanisms of obesity-induced gastrointestinal neoplasiaGenetic reduction of insulin-like growth factor-1 mimics the anticancer effects of calorie restriction on cyclooxygenase-2-driven pancreatic neoplasia.A novel strategy to inhibit FAK and IGF-1R decreases growth of pancreatic cancer xenograftsDual PI3K/mTOR Inhibitors Induce Rapid Overactivation of the MEK/ERK Pathway in Human Pancreatic Cancer Cells through Suppression of mTORC2.Interaction between IGF-1 polymorphisms and overweight for the risk of pancreatic cancer in Japanese.Hypoxia inducible factor-1 mediates effects of insulin on pancreatic cancer cells and disturbs host energy homeostasis.Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells.Regulation of cyclooxygenase-2 (COX-2) expression in human pancreatic carcinoma cells by the insulin-like growth factor-I receptor (IGF-IR) system.Toward a core nutraceutical program for cancer management.Does diabetes mellitus affect presentation, stage and survival in operable pancreatic cancer?Hypoxia and angiogenesis in pancreatic cancer.Current update of cytokines in pancreatic cancer: pathogenic mechanisms, clinical indication, and therapeutic values.The evaluation of the association between the metabolic syndrome and tumor grade and stage of bladder cancer in a Chinese population.Effect of insulin-like growth factor gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancerRAF kinase inhibitor-independent constitutive activation of Yes-associated protein 1 promotes tumor progression in thyroid cancerInsulin-like growth factor-1 receptor-targeted therapy for non-small cell lung cancer: a mini reviewAdaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.Molecular mechanism of pancreatic cancer--understanding proliferation, invasion, and metastasis.Glioblastoma, cancer stem cells and hypoxia.Emerging pathways and future targets for the molecular therapy of pancreatic cancer.Treatment options for advanced pancreatic cancer: a review.
P2860
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P2860
Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@ast
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@en
type
label
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@ast
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@en
prefLabel
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@ast
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@en
P2093
P2860
P921
P1476
Regulation of hypoxia-inducibl ...... oop in human pancreatic cancer
@en
P2093
Alexander A Parikh
Corazon D Bucana
Douglas B Evans
Lee M Ellis
Niels Reinmuth
Oliver Stoeltzing
Wenbiao Liu
P2860
P304
P356
10.1016/S0002-9440(10)63460-8
P407
P577
2003-09-01T00:00:00Z